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Hypotensive agent and method for producing the same

A technology of hypotensive agent and oligosaccharide, applied in the field of hypotensive agent and preparation thereof, can solve the problems of safety, high price and the like, and achieve the effects of low cost and convenient preparation

Inactive Publication Date: 2005-11-23
NAT INST OF ADVANCED IND SCI & TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The blood pressure-lowering agents used in the above-mentioned blood-pressure-lowering foods and medicines require a lot of raw materials, and many of them are expensive
In addition, as a daily use, some of them may bring safety and other issues

Method used

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  • Hypotensive agent and method for producing the same

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Embodiment

[0040] Embodiments of the present invention are described below. The raw materials, raw material consumption, ratio, processing conditions and processing sequence described in the embodiments can be appropriately changed without departing from the spirit and scope of the present invention. Therefore, the present invention should not be limitedly interpreted by the following examples.

[0041] (Oligosaccharides inhibit the activity of angiotensin-converting enzyme)

[0042] The antihypertensive activity of the oligosaccharide used in the present invention was studied by measuring the activity of inhibiting angiotensin converting enzyme (hereinafter referred to as the activity of inhibiting ACE). More specifically, the ACE-inhibiting activity of various oligosaccharides described below was analyzed.

[0043] 1) Glc(α1-1α)Glc: α, α-trehalose (sold by Wako Jun-yaku Company, product number KP7915);

[0044] 2) Glc(α1-1β)Glc: α, β-trehalose (sold by Sigma, product number T-0299);...

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Abstract

Disclosed is a hypotensive agent that is safe and inexpensive. The agent contains an oligosaccharide that comprises at least one type of hexose and has at least one 1-6 bond.

Description

technical field [0001] The invention relates to a hypotensive agent containing oligosaccharides, and a preparation method thereof. The oligosaccharides have a specific structure. Background technique [0002] High blood pressure has long been a problem. High blood pressure can lead to cerebral hemorrhage, heart disease, kidney disease, etc., so it is very important to prevent high blood pressure and inhibit its progress. Especially for older people, many times high blood pressure can cause serious problems. In addition, hypertension is currently a lifestyle-related disease that poses problems not only to the elderly but also to the young. [0003] JP-A 2002-272420 discloses an antihypertensive-related dietary composition comprising sodium alginate oligosaccharide as an active ingredient. [0004] The blood pressure-lowering agents used in the above-mentioned blood-pressure-lowering foods and medicines require a lot of raw materials, and many of them are expensive. In add...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7016A61K31/702A61K36/48A61P9/12C07H3/04C07H3/06
CPCA61K31/702A61K36/48C07H3/04A61K31/7016C07H3/06A61P9/12
Inventor 冈修一鹤田明稚河野泰广丸山进山崎幸苗菊池幸小野秀明
Owner NAT INST OF ADVANCED IND SCI & TECH
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