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Method for preparing extractive of dangshen polysaccharide as active ingredient, and preparation produced from the extractive

A technology of polysaccharides and active ingredients of Codonopsis pilosula, applied in the field of extracts of active ingredients of Codonopsis pilosula and its preparations, can solve problems such as unscientific preparation technology of oral liquid preparations, influence on the development and utilization of authentic medicinal materials in Shanxi, and loss of effective components, etc., and achieve improvement Purity and content, sufficient drug source, and the effect of saving ethanol

Inactive Publication Date: 2005-11-16
叶美曾
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AI Technical Summary

Problems solved by technology

In the 1970s, the oral liquid preparation of single-flavored Codonopsis pilosula was prepared by alcohol precipitation process, which could not be detected due to the absence of corresponding detection methods, resulting in the loss of active ingredients; The preparation process of water extraction and alcohol precipitation all leads to the loss of effective components
[0003] In terms of drug application, decoction pieces are mainly used for the compatibility of prescriptions and some Chinese patent medicines, and oral liquid preparations have faded out of the market due to reasons such as unscientific preparation processes that affect the curative effect, which has affected the further development and utilization of Shanxi authentic medicinal materials

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Codonopsis Codonopsis polysaccharide extract, the active ingredient of Codonopsis pilosula, can be obtained by the following method. Take 100Kg of Codonopsis pilosula raw material with clear quality standards, chop it into small pieces of 2-3cm, add 1000kg of pure water, decoct 2-3 times each time 2- After 3 hours, the combined filtrates were filtered, clarified, concentrated under reduced pressure to semi-fluid, specific gravity 1.25-1.26, and placed at 70-80°C for cooling. Centrifuge to obtain the precipitate and mother liquor, wash the precipitate twice with water, the weight of water is 1 / 3-1 / 4 of the wet precipitate, stir well, and centrifuge, dry the precipitate at 60-80°C to obtain a yellow powder Codonopsis polysaccharides, three mother liquors were combined, and the content of Codonopsis polysaccharides was determined to be above 2%.

Embodiment 2

[0027] Preparation of Dangshen Capsules: Take the Codonopsis polysaccharide extract powder with a content of more than 80%, fill it in medicinal capsules, seal the package, 0.5 grams per capsule (equivalent to 3 grams of raw materials), 1-2 times a day per adult , 3-4 capsules each time.

Embodiment 3

[0029] Preparation of Codonopsis granule: take 100 grams of Codonopsis polysaccharide powder with a content of 80%, mix with 400 grams of sucrose, pack it into bags (aluminum foil film), 10 grams per bag (equivalent to 15 grams of the original medicinal material Codonopsis pilosula), 1 bag each time for adults, 1 day 1-2 times, less for children.

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Abstract

A process for extracting the codonopsinose used to prepare the codonopsinose medicines in the form of infusion, capsule, syrup, or oral liquid includes cutting the pilose asiabell root, decocting 2-3 times, collecting filtered decoction, vacuum concentrating, cooling, centrifugal separation, drying the deposit, and pulverizing.

Description

technical field [0001] The invention relates to an extract of effective components of Chinese medicinal material Codonopsis pilosula and its preparation. Background technique [0002] Codonopsis Codonopsis is the first choice of traditional Chinese medicine clinically to invigorate the middle and replenish qi, invigorate the spleen and lungs, strengthen the body, nourish and strengthen the body, and anti-aging medicine. It is suitable for various diseases of spleen and lung qi deficiency. Extensive research has been carried out in clinical and clinical aspects, confirming that Codonopsis pilosula has many pharmacological effects, and has found a scientific basis for the theory of traditional Chinese medicine. Modern scientific methods have been used to conduct basic research on Codonopsis pilosula, and the active substance Codonopsis polysaccharides has been found. In the 1970s, the oral liquid preparation of single-flavored Codonopsis pilosula was prepared by alcohol precip...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08B37/00
Inventor 叶美曾郭小玲
Owner 叶美曾
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