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Chinese medicine compound formulation for treating rheumatism

A technology of compound preparations and traditional Chinese medicines, applied in the direction of medical formulas, non-central analgesics, medical preparations containing active ingredients, etc., can solve the problem of joint damage that cannot block the progression of rheumatism, and the content of active ingredients in drugs has not been determined. Regulations, poor compliance with medication, etc., to improve bioavailability, avoid adverse reactions, and reduce toxicity

Inactive Publication Date: 2005-10-05
四川倍达尔新技术开发有限公司
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  • Summary
  • Abstract
  • Description
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  • Application Information

AI Technical Summary

Problems solved by technology

(2) Induction palliative drugs, which have a slow onset of action and a long course of treatment, can alleviate the condition, but have relatively large side effects
(3) Although immunosuppressants (such as glucocorticoids, referred to as hormones) have powerful anti-inflammatory effects and can quickly relieve the symptoms of rheumatic patients, they cannot block the progression of rheumatism and progressive joint destruction, and long-term use The harm of side effects and iatrogenic diseases is not less than the harm of rheumatism itself, even greater than the harm of rheumatism itself
(2) Xiaohuoluo pills are big honeyed pills, with a daily dosage of 6g, which is a large dosage; the specification is 3g / tablet, which is very inconvenient to take, and the patient's medication compliance is poor
(3) In terms of quality control, Xiaohuoluo Pills only carried out microscopic identification of medicinal materials, and did not make regulations on the content of active ingredients of the medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Take Zhichuan Aconitum, Zhicaowu, Dilong, Frankincense, and Myrrh, and decoct them with water for 3 times, each time for 1.5 hours, for a total of 4.5 hours, filter, and centrifuge to obtain the supernatant. Concentrate the supernatant to a relative density of 1.2×10 3 kg / m 3 . In addition, Dannanxing is crushed into fine powder, used as base material and extract for spray granulation, granulation, and sterilization, and then adopts the existing capsule preparation process to prepare the capsule of the drug of the present invention. After testing, the effective drug content of 1 gram of the capsule drug is equivalent to the effective drug content of 3-6 grams of the original Xiaohuoluo pill.

Embodiment 2

[0037] Take Zhichuan Aconitum, Zhicaowu, Dilong, Frankincense, and Myrrh, and decoct them with water for 3 times, 1 hour each time, for a total of 3 hours, filter, and centrifuge to obtain the supernatant. Concentrate the supernatant to a relative density of 1.1×10 3 kg / m 3 . Separately take Dannanxing and crush it into fine powder, use it as a base material and extract for granulation, granulation, and sterilization, and then adopt the existing granule preparation process to prepare the granule of the drug of the present invention.

Embodiment 3

[0039] Take Zhichuan Aconitum, Zhicaowu, Dilong, Frankincense, and Myrrh, and decoct them with water for 3 times, 3 hours each time, for a total of 9 hours, filter, and centrifuge to obtain the supernatant. Concentrate the supernatant to a relative density of 1.3×10 3 kg / m 3 . In addition, Dannanxing is crushed into fine powder, used as base material and extract, granulated, granulated, and sterilized, and then the existing tablet preparation process is used to obtain the tablet of the drug of the present invention.

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Abstract

The present invention relates to a Chinese medicine compound preparation for curing stagnation-syndrome of qi and blood. Said Chinese medicine compound preparation is made up by using 5 Chinese medicinal materials of prepared aconite main tuber, prepared wild aconite tuber, earth worm, frankincense and myrrh through a certain preparation process.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation for treating arthralgia. Background technique [0002] The category of arthralgia in traditional Chinese medicine is similar to the rheumatism category of autoimmune diseases in modern medicine, such as rheumatoid arthritis, rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, especially rheumatoid arthritis, rheumatoid arthritis Two diseases are common. Commonly used drugs for the treatment of rheumatism in Western medicine mainly include (1) non-steroidal drugs, which have anti-inflammatory, antipyretic, and analgesic effects. There are often adverse reactions such as gastrointestinal inflammation, bleeding or ulcers. (2) Induction palliative drugs, which have a slow onset and a long course of treatment, can alleviate the condition, but have relatively large side effects. (3) Although immunosuppressants (such as glucocorticoids, referred to as hormones) have powe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/16A61K9/20A61K9/48A61P19/00A61P19/02A61P29/00
Inventor 李存勇黄衡
Owner 四川倍达尔新技术开发有限公司
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