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Medicine for treating cerebrovascular and cardiovascular diseases and preparation process thereof

A technology of cardiovascular and cerebrovascular diseases and production technology, which is applied in the field of traditional Chinese medicine to achieve the effects of convenient use, enhanced immunity and low price

Active Publication Date: 2004-11-10
GUANGDONG SHUNFENG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report on the compound preparation of Danshenpuerarin

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Embodiment 1 (preparation of injection)

[0019] In a local 100-level sterile clean GMP workshop, weigh 10 mg of danshensu, catechin aldehyde, 100 mg of puerarin, and appropriate amount of excipients according to the formula. The needles are adsorbed with charcoal for 10-20 minutes, decarbonized, sterilized by filtration with a 0.2μ microporous membrane, aseptically filled, freeze-dried in a freeze dryer until the water content is less than 5%, plugged, capped, light inspected, After testing, labeling and packaging, the freeze-dried powder for injection is obtained.

Embodiment 2

[0020] Embodiment 2 (preparation capsule)

[0021] Each capsule contains:

[0022] Danshensu, catechin 15mg

[0023] Puerarin 150mg

[0024] Excipients (lactose, etc.) Appropriate amount

[0025] In a GMP workshop with a relative humidity below 45%, weigh danshensu, catechin aldehyde, puerarin, and auxiliary materials according to the formula, mix them in a three-dimensional mixer for 30 minutes, and pulverize them into sub-nanometer powders with a supersonic jet mill, and then place Mix in a three-dimensional mixer for 30 minutes, then pack into No. 3 capsules with a high-speed automatic capsule filling machine, polish, and pack in aluminum and plastic.

[0026] Usage and dosage: 1-2 capsules each time, 1-2 times a day.

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PUM

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Abstract

The invention relates to a medicament for treating cerebrovascular diseases and process for preparation, wherein the medicament is prepared from high purity radix salvia miltiorrhiza, catechu aldehyde and puerarin through the steps of purifying, mixing, preparing sub-nano grade powder, filtering, degerming, packaging, detecting, and obtaining medicine with high biological availability.

Description

(1) Technical field [0001] The invention relates to a medicine for treating cardiovascular and cerebrovascular diseases and a production process thereof, which is a secondary development technology of a Chinese patent medicine and belongs to the technical field of traditional Chinese medicine. (2) Background technology [0002] Cardiovascular disease is one of the most serious diseases that threaten human beings in the world today. Its morbidity and mortality have surpassed tumor diseases and ranked first in the world. In the United States, more than 57.5 million people suffer from more than one cardiovascular disease. Diseases, of which 50 million had hypertension; 13.7 million had myocardial infarction; 7.1 million had angina; 4.8 million had congestive heart failure and 4.5 million had arrhythmia. More than 2,600 Americans die from cardiovascular disease every day, making it the number one cause of death in the United States. [0003] With the control of infectious disea...

Claims

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Application Information

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IPC IPC(8): A61K31/7048A61P3/06A61P9/00A61P9/10A61P9/12
Inventor 刘贤英林文红
Owner GUANGDONG SHUNFENG PHARMA
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