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Oil from momordica charantia L., its method of preparation and uses

A kind of bitter gourd seed, selected technology, applied in vasodilator and wound healing agent, anti-arthritis, as anti-inflammatory field, can solve problems such as no report of bitter gourd extract oil etc.

Inactive Publication Date: 2002-07-31
MAGNA MISSION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Likewise, there is no report in the literature on the extraction of oil from bitter melon

Method used

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  • Oil from momordica charantia L., its method of preparation and uses
  • Oil from momordica charantia L., its method of preparation and uses
  • Oil from momordica charantia L., its method of preparation and uses

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Embodiment 1 (oil preparation embodiment)

[0049] Extract oil from bitter melon:

[0050] Take 100 grams of dried seeds from the ripe fruit of bitter melon. Split the seed. The dehisced seeds are then washed well with water 3-4 times to free them from substantially all impurities. The seeds were then vacuum dried and pulverized into a fine powder using a milling device.

[0051] Any other conventional means may also be used. This is followed by treatment with acetone-hexane solvent at a mixing ratio of 1:2. The mixture was stirred well and allowed to stand at room temperature for 48 hours. Separate the oil layer. The oil that separated was collected as a clear layer. The oil is then treated with 2-5% zinc acetate dissolved in water so that salts, last traces of protein and other impurities are precipitated. The oil was centrifuged and analyzed by gas liquid chromatography. Oil purified by gas-liquid chromatography was shown to contain the following fatty acids...

Embodiment 2

[0060] Embodiment 2: extract oil from bitter gourd

[0061] Take 200 grams of dried seeds from the ripe fruit of bitter melon. Split the seed. The split seeds are then thoroughly washed with water 3-4 times so that they are substantially free of all impurities. These seeds were then vacuum dried and pulverized into a fine powder using a milling device.

[0062] Any other conventional means may also be used. This fine powder was then treated with acetone benzene solvent in a mixing ratio of 1:2. This mixture was stirred well and allowed to stand at room temperature for 48 hours. The oil in this liquid layer was separated using a separatory funnel. The filtrate was heated at reflux with acetone-benzene, and this step was repeated 2-3 times to separate the last traces of oil. The oil which separated out as a supernatant layer was collected. The oil is then treated with 2-5% zinc acetate in water so that salts, last traces of protein and other impurities are precipitated. ...

Embodiment 3

[0073] Embodiment 3: the preparation of oil composition

[0074] The oil extracted from Momordica charantia was kept in a beaker as discussed in Preparative Examples 1-3. Add pure sesame oil to it in a ratio of 3:1. The mixture was continuously and thoroughly stirred for 4-10 hours. Thereafter, aromatic oils such as sandalwood oil and fragrance ingredients are added to the mixture and stirred continuously and thoroughly for 4-10 hours. The preparations thus prepared are stored in containers in a dry and cool place.

[0075] The oil compositions of the present invention may be formulated in a variety of physical forms including solutions, lotions, creams, oils, gels, sticks, sprays, ointments, balms, pastes, aerosols, and the like.

[0076] For formulation in ointments, the active ingredients of such oil compositions may be incorporated into any pharmacologically acceptable carrier, which is suitable for topical administration to human skin. Likewise, such pharmacologically...

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PUM

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Abstract

The present invention relates to a novel oil extracted from the seeds of Momordica charantia L., for topical application to a body of mammal and used as anti-inflammatory, anti-arthritic, vasculodilatory and wound healing agent, said oil essentially comprising caprice acid 0.7-1.2% by wt., lauric acid 0.6-1% by wt., palmitic acid 4.2-5.0% by Wt,, stearic acid 59-62% by wt., oleic acid 13-15% by wt., archid acid 3-5 % by wt., linoleic acid 8-10% by wt., and other undetected minor acids 6-8 % by wt.; and a process for producing such oil.

Description

field of invention [0001] The present invention generally relates to a novel oil extracted from the seeds of Momordica bitter melon (Bitter gourd), its formulation and use as an anti-inflammatory, anti-arthritic, vasculodilatory and wound-healing agent. Background technique [0002] The present invention relates to a novel oil extracted from the seeds of Bitter Gourd (Bitter Gourd). Bitter melon is a perennial herb of Cucurbitaceae that grows widely in Asia. This herb is native to tropical countries such as India, South Africa, the Philippines, China and Myanmar. Momordica found in Western countries differs from tropical species in that the plants differ in morphology and organoleptic properties. Various parts of this plant, especially the fruit, have been widely used in the preparation of hypoglycemic pharmaceutical compositions. [0003] The extract / juice of this fruit is known to exhibit hypoglycemic properties and is often recommended for lowering blood sugar levels i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/00A61K36/185A61K36/42A61K36/48A61K36/53A61K36/63A61K36/738A61K36/886
CPCA61K36/738A61K36/48A61K36/63A61K36/53A61K36/886A61K36/42A61K36/185A61P19/02A61K2300/00A61K8/97A61K31/201
Inventor 普什帕康纳
Owner MAGNA MISSION
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