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Traditional Chinese medicine for treating aplastic anemia and its preparation process

An aplastic, traditional Chinese medicine technology, used in medical preparations containing active ingredients, blood diseases, drug combinations, etc., can solve the problems of limited clinical application, poor efficacy, and non-lasting efficacy, and achieve the promotion of hormone receptor affinity in the body. , Bone marrow hematopoietic function recovery, the effect of promoting proliferation and differentiation

Inactive Publication Date: 2006-09-13
武汉芄焓药物研发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the treatment of aplastic anemia at home and abroad is nothing more than the following types of drugs: First, androgen and cyclosporin are the most commonly used drugs for the treatment of aplastic anemia today, but both have different degrees. Toxic and side effects have greatly restricted its clinical application
Second, GM-CSF, EPO, IL-3 and other cytokines have been used in the treatment of aplastic anemia in recent years, but the curative effect is not long-lasting, and the price is expensive, so it is not the first choice for treatment
Third, Chinese patent medicines are used to treat aplastic anemia, such as Aplastic anemia Shengxue Tablets, Shengxue Pills, Compound Zaofan Pills, etc., but these Chinese patent medicines mainly have the functions of nourishing yin, reducing fire, and nourishing the spleen, and benefiting the spleen. The efficacy of marrow blood production is poor, so most of them can only improve the clinical symptoms of patients, while the clinical treatment effect is not good, the effective rate is only 30-50%, and patients still have to rely on Western medicine such as cyclosporine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Embodiment 1: take raw material (kilogram) by following weight ratio:

[0045] Red ginseng root 25 Astragalus 8 Rehmannia glutinosa 8

[0046] Cuscuta 8 Antler slices 8 Roasted tortoise shell 8

[0047] Lycium barbarum 8 Psoralen 8 Cooked aconite 8

[0048] Cinnamon 2.

Embodiment 2

[0049] Embodiment 2: take raw material (kilogram) by following weight ratio:

[0050] Red ginseng root 30 Astragalus 9 Rehmannia glutinosa 9

[0051] Cuscuta 9 Antler slices 9 Roasted tortoise shell 9

[0052] Lycium barbarum 9 Psoralen 9 Cooked aconite 9

[0053] Cinnamon 3.

Embodiment 3

[0054] Embodiment 3: take raw material (kilogram) by following weight ratio:

[0055] Red ginseng root 35 Astragalus root 12 Rehmannia glutinosa 12

[0056] Cuscuta 11 Antler slices 11 Roasted tortoise shell 11

[0057] Lycium barbarum 10 Psoralen 14 Cooked aconite 9

[0058] Cinnamon 5.

[0059] Its preparation process is as follows: according to the weight ratio in the above examples, add water to decoct ten traditional Chinese medicine raw materials of red ginseng root, astragalus root, rehmannia glutinosa, dodder seed, antler slices, roasted tortoise shell, wolfberry fruit, psoralen, cooked aconite and cinnamon Twice, adding 7 times the weight of the raw material to decoct for 45 minutes each time, and merging the filtrates decocted twice. The combined filtrate is then concentrated to a relative density of 1.15 (measured at a temperature of 90° C.), adding ethanol to the filtrate with an alcohol content of 55%, ethanol precipitation for more than 24 hours, reclaiming et...

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PUM

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Abstract

The invention discloses a medicinal Chinese medicine for curing regenerative obstructive anaemia and its preparing technique, prepared in proportion of red ginseng tails, Radix astragali, Radix rehmanniae preparata, dodder seed, alter slice, moxibustion tortoise plastron, medlar, Malaytea Scurfpea Fruit, Prepared Common Monkshood Daughter Root, and cinnamon. And the preparing technique: decocting the above ten raw materials twice and combining the two filtrates; then concentrating, alcohol-depositing, cooling to room temperature and making into cream; drying the cream and then making powder spraying and filling into capsules; or adding dextrin or starch to the cream to make into soft material, and finally screening and drying the soft material to make into electuary or tablets. It can not only regulate mediation disorder of human immunity, stimulate the hemopoiesis recovery of human marrow, and have remarkable curative effect on the regenerative obstructive anaemia but also has considerably good curative effect on other refractory anaemias, as well as the symptoms caused by various reasons, such as marrow inhibition, blood cell reduction, etc. And it almost has no toxicity and side effect, safe and reliable, low-cost.

Description

technical field [0001] The invention relates to a kidney-tonifying and marrow-reinforcing medicament prepared from Chinese herbal medicines, in particular to a traditional Chinese medicine for treating aplastic anemia and a preparation process thereof. Background technique [0002] Aplastic anemia, as a disease of hematopoietic pararegulatory hyperactivity, has become a common disease of the blood system with great harm. Clinically, it is mainly chronic, protracted, and extremely difficult to treat. So far, there is no ideal drug, which makes clinicians feel difficult. Especially in recent years, with the emergence of the national house decoration upsurge, people are more and more likely to be in contact with harmful chemical decoration materials, resulting in an increase in the incidence of aplastic anemia in my country year by year, and there is a trend of younger patients, so There is an urgent need for a safe and reliable new drug for treatment. ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/815A61K36/804A61K36/714A61K36/54A61K36/487A61K36/481A61K36/39A61K36/258A61K35/56A61K35/32A61K9/14A61K9/20A61K9/48A61P7/06A61K35/586
Inventor 徐靖
Owner 武汉芄焓药物研发有限公司
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