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Traditional Chinese medicine compound composition for treating male oligoasthenospermia as well as preparation method and application of traditional Chinese medicine compound composition

A technique for asthenozoospermia and composition, which is applied in the field of traditional Chinese medicine compound composition and its preparation, can solve problems such as poor surgical results, and achieve the effects of definite medication curative effect, improving sperm motility, and increasing male sexual function

Active Publication Date: 2022-05-31
NANJING MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Assisted reproductive technology can help patients have their own children. Since assisted reproductive technology also requires completely normal sperm to be successful, it is not effective for patients with severe oligoasthenospermia.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] The traditional Chinese medicine compound composition for treating oligoasthenozoospermia consists of the following raw materials in parts by mass:

[0038] 10 parts of raw land, 10 parts of rehmannia, 15 parts of medlar, 15 parts of sand garden fruit, 10 parts of Nansha ginseng, 10 parts of northern sand ginseng, 10 parts of asparagus, 10 parts of Ophiopogon japonicus, 10 parts of schisandra, 15 parts of mulberry fruit, raspberry 15 parts, 10 parts of paeonol, 10 parts of Danshen, 10 parts of Achyranthes bidentata, 10 parts of Achyranthes bidentata, 10 parts of Dipsacus, 10 parts of Xiejisheng, 15 parts of Cuscuta, 15 parts of Polygonatum, and 10 parts of Eucommia.

[0039] Preparation:

[0040] Weigh the raw materials according to the above mass, mix to obtain the mixture, add 80% ethanol solution (the volume ratio of the mixture to ethanol is 1:10), reflux extraction 3 times, each extraction 90min, combine the extracts, filter, and filtrate Concentrate under reduced...

Embodiment 2

[0043] The traditional Chinese medicine compound composition for treating oligoasthenozoospermia consists of the following raw materials in parts by mass:

[0044] 20 parts of raw land, 20 parts of rehmannia, 30 parts of wolfberry fruit, 30 parts of sand garden fruit, 20 parts of Nansha ginseng, 20 parts of northern sand ginseng, 20 parts of asparagus, 20 parts of Ophiopogon japonicus, 15 parts of schisandra, 30 parts of mulberry fruit, raspberry 30 parts, 20 parts of paeonol, 20 parts of salvia, 15 parts of Sichuan Achyranthes bidentata, 15 parts of Achyranthes bidentata, 20 parts of Dipsacus, 20 parts of mistletoe, 30 parts of dodder seed, 30 parts of Polygonatum, and 20 parts of Eucommia.

[0045] Preparation:

[0046] Weigh the raw materials according to the above mass, mix to obtain the mixture, add a 50% ethanol solution (the volume ratio of the mixture to ethanol is 1:10), reflux extraction 3 times, each extraction 60min, combine the extracts, filter, the filtrate Conc...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine compound composition for treating male oligoasthenospermia as well as a preparation method and application of the traditional Chinese medicine compound composition. The traditional Chinese medicine compound composition is prepared from the following raw materials: radix rehmanniae, radix rehmanniae preparata, fructus lycii, semen astragali complanati, radix adenophorae, radix glehniae, radix asparagi, radix ophiopogonis, fructus schisandrae chinensis, mulberry, raspberry, cortex moutan, radix salviae miltiorrhizae, radix cyathulae, radix achyranthis bidentatae, radix dipsaci, mistletoe, semen cuscutae, rhizoma polygonati and cortex eucommiae. The traditional Chinese medicine compound composition has the functions of increasing male sexual function and gonadotropin synthesis or secretion, can obviously improve semen quality, increase sperm quantity, increase sperm motility and the like, has no adverse reaction clinically, and is definite in medication curative effect.

Description

technical field [0001] The invention relates to a compound traditional Chinese medicine, in particular to a compound traditional Chinese medicine composition for treating male oligoasthenozoospermia and its preparation method and application. Background technique [0002] Infertility is not only a disease but also a bio-psycho-social health problem. With social pressure and changes in people's lifestyles, there are more and more infertility patients; it has attracted widespread attention. About 5% of couples in the world are infertile, of which male infertility accounts for more than half of all infertility. Therefore, the research on male infertility should be paid more attention. Male infertility can be divided into two types, primary and secondary, with various etiologies, mainly including congenital or acquired genitourinary system abnormalities, genitourinary tract infection, elevated scrotal temperature caused by varicocele, and malignant tumors , endocrine disorder...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P15/08A61P15/00
CPCA61K36/804A61K36/815A61K36/481A61K36/342A61K36/23A61K36/8965A61K36/8968A61K36/79A61K36/57A61K36/605A61K36/73A61K36/71A61K36/65A61K36/537A61K36/21A61K36/185A61K36/39A61K36/43A61K36/8969A61K36/46A61P15/08A61P15/00A61K2236/333A61K2236/39A61K2300/00Y02A50/30
Inventor 章茂森胡志斌刁飞扬孙秀兰林苑
Owner NANJING MEDICAL UNIV
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