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Bacteriostatic granulation-promoting ointment dressing and preparation method thereof

An ointment and muscle-building technology, used in bandages, absorbent pads, and resistance to vector-borne diseases, etc., can solve problems such as deficiency, wounds cannot produce metabolic functions, and wounds are difficult to heal, achieve good affinity, increase wound healing, Wide range of antibacterial effects

Inactive Publication Date: 2022-05-27
李世平
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, many auxiliary materials lack the corresponding antibacterial and anti-inflammatory mixed dressing ingredients, resulting in the use of some wounds due to bacterial infection, causing the wounds to fail to produce metabolic functions, making it difficult for wounds to heal. Medical dressings came into being. Medical dressings are used for wounds. Repair, wound healing and hemostasis, mainly related to postoperative wound management
[0004] The current research direction is mainly to improve the compatibility and antibacterial properties of dressings with the wound surface, but how to effectively use traditional auxiliary materials to treat existing dressings with antibacterial properties and improve the wound healing effect remains to be further studied

Method used

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  • Bacteriostatic granulation-promoting ointment dressing and preparation method thereof
  • Bacteriostatic granulation-promoting ointment dressing and preparation method thereof
  • Bacteriostatic granulation-promoting ointment dressing and preparation method thereof

Examples

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preparation example Construction

[0041] A preparation method of a bacteriostatic and muscle-building ointment dressing, the preparation method comprising the following steps:

[0042] Step 1: Mix β-cyclodextrin with deionized water, heat to dissolve it, and obtain a saturated aqueous solution of β-cyclodextrin;

[0043] Step 2: prepare emulsion type ointment base;

[0044] A. Mix carbolic acid with lanolin, white petrolatum, liquid paraffin and sodium hyaluronate into a container, heat, mix and melt in a constant temperature water bath device at 110-120°C, and keep warm to obtain the first mixture;

[0045] B, the polyhexamethylene guanidine of 1 / 2 amount, alginic acid are mixed and placed on the constant temperature water bath and heated and mixed, add the cypress oil and stir, insulation, obtains the second mixture;

[0046] Step 3: graft-copolymerizing the remaining 1 / 2 amount of polyhexamethylene guanidine and chitosan in step 2 to form modified chitosan;

[0047] Step 4: preparing the chitosan modified...

specific Embodiment 1

[0058] A bacteriostatic and muscle-building ointment dressing, the raw materials of the dressing formulation components include ointment base, beta-cyclodextrin, cypress oil, polyhexamethylene guanidine, alginic acid, calcium and silver phosphate, petrolatum, liquid paraffin, transparent sodium phosphate;

[0059] 10 parts of ointment base, 10 parts of beta-cyclodextrin, 6 parts of cypress oil, 10 parts of polyhexamethylene guanidine, 8 parts of alginic acid, 10 parts of calcium silver phosphate, 5 parts of petrolatum, 5 parts of liquid paraffin, hyaluronic acid 7 parts sodium.

[0060] The preparation method thereof comprises the following steps:

[0061] Step 1: Mix β-cyclodextrin with deionized water, heat to dissolve it, and obtain a saturated aqueous solution of β-cyclodextrin;

[0062] Step 2: prepare emulsion type ointment base;

[0063] A. Mix carbolic acid with lanolin, white petrolatum, liquid paraffin and sodium hyaluronate into a container, heat, mix and melt in...

specific Embodiment 2

[0075] A bacteriostatic and muscle-building ointment dressing, the raw materials of the dressing formulation components include ointment base, beta-cyclodextrin, cypress oil, polyhexamethylene guanidine, alginic acid, calcium and silver phosphate, petrolatum, liquid paraffin, transparent sodium phosphate;

[0076] 15 parts of ointment base, 8 parts of β-cyclodextrin, 3 parts of cypress oil, 6 parts of polyhexamethylene guanidine, 2 parts of alginic acid, 3 parts of calcium silver phosphate, 5 parts of petrolatum, 5 parts of liquid paraffin, hyaluronic acid 7 parts sodium.

[0077] The preparation method thereof comprises the following steps:

[0078] Step 1: Mix β-cyclodextrin with deionized water, heat to dissolve it, and obtain a saturated aqueous solution of β-cyclodextrin;

[0079] Step 2: prepare emulsion type ointment base;

[0080] A. Mix carbolic acid with lanolin, white petrolatum, liquid paraffin and sodium hyaluronate into a container, heat, mix and melt in a con...

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Abstract

The invention discloses an ointment dressing capable of inhibiting bacteria and promoting tissue regeneration and a preparation method thereof. The raw materials of formula components of the dressing comprise an ointment matrix, beta-cyclodextrin, Chinese juniper oil, polyhexamethylene guanidine, alginic acid, calcium phosphate silver, vaseline, liquid paraffin and sodium hyaluronate. The ointment is prepared from the following raw materials in parts by weight: 10-15 parts of ointment matrix, 3-10 parts of beta-cyclodextrin, 2-6 parts of juniper oil, 6-10 parts of polyhexamethylene guanidine, 2-8 parts of alginic acid, 3-10 parts of calcium silver phosphate, 2-5 parts of vaseline, 2-5 parts of liquid paraffin and 3-7 parts of sodium hyaluronate. The ointment matrix is composed of the mixture of the carbolic acid and the lanolin, the mixing ratio of the carbolic acid to the lanolin is 2: 1, and the different proportions can fully reflect that the mixed matrix of the carbolic acid and the lanolin has good antibiosis and can lubricate the skin and promote the combined healing of the skin.

Description

technical field [0001] The invention relates to the technical field of medical dressings, in particular to a bacteriostatic and muscle-building ointment dressing and a preparation method thereof. Background technique [0002] Ointment is a semi-solid external preparation with a certain consistency made by uniformly mixing a drug and a suitable matrix. As a convenient and fast external preparation with good transdermal effect, cream has a wide range of applications in people's daily life and in the field of medicine. . O / W type ointment base is widely used in ointment because it has the advantages of refreshing and non-greasy, easy to clean and fast drug release; [0003] At present, there is a lack of corresponding antibacterial and anti-inflammatory mixed dressing ingredients in many accessories. As a result, some wounds cannot produce metabolic function due to bacterial infection, which makes the wound difficult to heal. Medical dressings came into being. Medical dressing...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00A61L15/18A61L15/20A61L15/28A61L15/46A61L15/34
CPCA61L26/0057A61L26/0066A61L26/0004A61L26/0023A61L26/0061A61L15/18A61L15/20A61L15/28A61L15/46A61L15/34A61L2300/30A61L2300/404C08L5/04Y02A50/30
Inventor 李世平
Owner 李世平
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