Method and system for separating and detecting VOCs (Volatile Organic Chemicals) gas in human respiratory signs and application
A detection method and detection system technology, which is applied in the field of respiratory detection of human chronic diseases, can solve the problems of large analysis time consumption, expensive and bulky equipment, and achieve the effect of reducing detection cost and time, and high-precision gradient heating
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[0067] The sample mixed VOCs gases in this embodiment are pentane, acetone, toluene, octane and decane, the concentration of each component is 16ppm, and the balance gas is air. VOCs in the breath are composed of alkanes, alcohols, ketones, etc., and some gas biomarker patterns are helpful for the diagnosis of related endogenous diseases. At the same time, exhaled gas is a mixture with a wide boiling point, which should also be considered in practical applications. Therefore, a panel of five VOCs biomarkers (boiling point range from 36.1 °C to 174.8 °C) that may be considered as common endogenous diseases was selected to verify the analytical performance of the compact gas chromatography prototype. Pentane is a product of lipid peroxidation of polyunsaturated fatty acids in cell membranes, and its concentration is significantly elevated in patients with nonalcoholic fatty liver disease. Toluene, a compound that occurs in everyone's exhaled breath, was found in slightly higher...
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