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System and method for camera-based quantification of blood biomarker

A biomarker and blood technology, applied in the field of blood biomarker detection, can solve the problems of invasiveness, limited use, and expensive blood panels

Pending Publication Date: 2022-04-29
NURALOGIX CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Blood panels are often expensive, invasive, and uncomfortable, limiting their use in frequent monitoring applications
Also, these panels may take several days to get results

Method used

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  • System and method for camera-based quantification of blood biomarker
  • System and method for camera-based quantification of blood biomarker
  • System and method for camera-based quantification of blood biomarker

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Embodiment Construction

[0039] Embodiments will now be described with reference to the figures. For simplicity and clarity of illustration, where considered appropriate, reference numerals may be repeated among the figures to indicate corresponding or analogous elements. Additionally, numerous details are set forth in order to provide a thorough understanding of the embodiments described herein. However, it will be understood by those skilled in the art that the embodiments described herein may be practiced without these details. In other instances, well-known methods, procedures, and components have not been described in detail so as not to obscure the embodiments described herein. Moreover, the description is not to be considered as limiting the scope of the embodiments described herein.

[0040]Unless the context dictates otherwise, the various terms used throughout this description of the present invention can be read and understood as follows: use of "or" throughout is inclusive, as if written...

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Abstract

The present invention provides systems and methods for determining the concentration of one or more blood biomarkers in a human subject. The method includes determining, using a first machine learning model trained by a hemoglobin concentration (HC) change training set, bit values representing the HC change in the subject from a set of bit planes in a sequence of captured images, the set of bit planes being those determined to approximately maximize a signal-to-noise ratio (SNR), the HC change training set comprises bit values of each bit plane from images captured from a set of subjects with known HC changes; the concentration of one or more blood biomarkers is determined using a second machine learning model trained with a blood biomarker training set that includes previously determined HC change signals from other subjects and one or more blood panels from those subjects as base true data.

Description

[0001] field of invention [0002] The following generally relates to detection of blood biomarkers, and more specifically, to systems and methods for camera-based quantification of blood biomarkers. Background technique [0003] A blood panel is the scientific analysis of a blood sample. Samples are usually collected from a vein by a professional using a hypodermic needle or by pricking a finger. A panel is usually a series of tests used to precisely quantify a specific blood component. Blood panels are important tools in healthcare for determining physiological and biochemical states such as disease, mineral content, drug efficacy, organ function, and more. Blood panels are often expensive, invasive, and uncomfortable, which limits their use in frequent monitoring applications. Also, it may take several days for these types of panels to produce results. Contents of the invention [0004] In one aspect, there is provided a method for determining the concentration of one...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/1455G06N20/00G06N3/02
CPCG06N20/20G06N20/10A61B5/14551A61B5/0075A61B5/14532G06N3/048G06N3/044A61B5/1455
Inventor 李康安德鲁·巴什奇克伍思嘉尤塞夫·雅辛温斯顿·德阿马斯艾伦·丁
Owner NURALOGIX CORP
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