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Method and device for generating deliverable radiotherapy plan according to three-dimensional space dose distribution

A technology of dose distribution and three-dimensional space, which is applied in radiation therapy, X-ray/γ-ray/particle irradiation therapy, treatment, etc., can solve the problems of limited application range, and achieve the effect of wide application range and high efficiency

Pending Publication Date: 2022-01-18
程明霞
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, this method of directly predicting the fluence map has a very limited application range.

Method used

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  • Method and device for generating deliverable radiotherapy plan according to three-dimensional space dose distribution
  • Method and device for generating deliverable radiotherapy plan according to three-dimensional space dose distribution
  • Method and device for generating deliverable radiotherapy plan according to three-dimensional space dose distribution

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Embodiment 1

[0037] figure 1 is a schematic flowchart of a method for generating a deliverable radiotherapy plan according to a three-dimensional dose distribution in an embodiment of the present invention.

[0038] like figure 1 As shown, this embodiment first acquires patient-related data to be used to generate a deliverable radiotherapy plan; then, preprocesses the acquired patient-related data according to a preset algorithm; then, based on the preset field dose prediction model and The preprocessed patient-related data predicts the field dose in each field direction; then, predicts the fluence map in each field direction based on the preset fluence map prediction model and field dose; finally, based on the predicted fluence map and radiotherapy The parameters of the equipment generate a deliverable plan. Overall, it includes five processes: acquiring data, preprocessing, predicting field dose, predicting fluence map, and generating a deliverable radiotherapy plan.

[0039] figure...

Embodiment 2

[0092] Figure 13 is a schematic diagram of a method for generating a deliverable radiotherapy plan according to a three-dimensional spatial dose distribution according to an embodiment of the present invention.

[0093] like figure 1 and Figure 13 As shown, compared with the first embodiment, this embodiment further includes the step of generating a BEV dose map based on the predicted field dose.

[0094] In the first embodiment, step S4 is: predict based on the preset fluence map prediction model and the field dose in each field direction, and obtain the fluence map in each field direction.

[0095] Step S4 of the present embodiment (that is, the step of fluence map prediction) is carried out according to the following sub-steps:

[0096] Step S4-1, reconstructing the field dose in each field direction into a three-dimensional distribution, and projecting it along the BEV direction to generate a two-dimensional BEV dose map to be processed in each field direction;

[00...

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Abstract

The invention provides a method for generating a deliverable radiotherapy plan according to three-dimensional space dose distribution. The method comprises the following steps of preprocessing obtained patient radiotherapy related data used for generating the deliverable radiotherapy plan, and predicting a field dose in each radiation field direction through a preset field dose prediction model; and further based on the predicted field dose, predicting a fluence map of each corresponding radiation field direction through a preset fluence map prediction model, and finally, generating a deliverable radiotherapy plan based on the predicted fluence map of each radiation field direction and radiotherapy equipment parameters, wherein the generated deliverable radiotherapy plan comprises the information of each radiation field direction and related parameters of an accelerator, so that the generated deliverable radiotherapy plan is the deliverable plan which can be executed by a radiotherapy accelerator. Since a deep convolutional neural network is adopted to predict the field dose and the fluence map, the dosimetry features of original three-dimensional space dose distribution are reserved through a high-dimensional feature automatic extraction mode, dose fidelity before and after conversion is high, and generation speed is high.

Description

technical field [0001] The invention belongs to the field of radiotherapy, relates to radiotherapy plan design for radiotherapy, and in particular relates to a method and device for generating a deliverable radiotherapy plan according to three-dimensional spatial dose distribution. Background technique [0002] Radiation therapy (radiotherapy) is one of the main treatments for cancer. Radiation therapy uses ionizing radiation such as high-energy X-rays, gamma rays, electrons, and proton heavy ions to kill tumor tissues in the body. Before implementing radiotherapy irradiation, it is necessary to design a radiotherapy plan to simulate the dose distribution in the body, that is, to give the tumor site a high irradiation dose as accurately as possible, and at the same time protect the normal organs around the tumor as much as possible. Normal tissues or normal organs should be given low radiation doses as much as possible. In order to better meet this requirement, the design ...

Claims

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Application Information

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IPC IPC(8): A61N5/10
CPCA61N5/103A61N5/1039A61N5/1064
Inventor 程明霞
Owner 程明霞
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