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Application of tectorigenin A in preparation of medicine for preventing and treating bronchial asthma disease

A technology of iris flavin and bronchial asthma, which is applied in drug combinations, respiratory diseases, pharmaceutical formulations, etc., can solve problems such as drug resistance and affecting the quality of life of patients, reduce airway inflammatory factors, and improve airway High responsiveness, inflammation control effect

Pending Publication Date: 2021-11-05
新疆维吾尔医学专科学校
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the long-term use of such drugs will lead to drug resistance, which will seriously affect the quality of life of patients in the later stage.

Method used

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  • Application of tectorigenin A in preparation of medicine for preventing and treating bronchial asthma disease
  • Application of tectorigenin A in preparation of medicine for preventing and treating bronchial asthma disease
  • Application of tectorigenin A in preparation of medicine for preventing and treating bronchial asthma disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Example 1: The application of a kind of iris flavin A in the preparation of medicine for preventing and treating bronchial asthma.

Embodiment 2

[0020] Example 2: As an optimization of the above example, iris flavin A is extracted from the Chinese medicinal material Shegan.

Embodiment 3

[0021] Example 3: As an optimization of the above example, the drug is obtained by loading irisflavin A in any pharmaceutically acceptable dosage form.

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PUM

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Abstract

The invention relates to the technical field of tectorigenin A, in particular to application of tectorigenin A in preparation of a medicine for preventing and treating bronchial asthma. The invention discloses the application of tectorigenin A in preparation of the medicine for preventing and treating bronchial asthma for the first time, tectorigenin A not only can effectively reduce the pulmonary airway resistance of a model mouse and improve the airway hyperreactivity of the model mouse, but also can reduce the number of total leukocytes, monocytes and basophilic granulocytes in alveolar lavage fluid of the model mouse, so that the number of total leukocytes, monocytes and basophilic granulocytes in the alveolar lavage fluid of the model mouse is reduced. The invention can be used for effectively treating bronchial asthma, effectively controlling inflammation and remarkably reducing airway inflammatory factors IL-4 and IL-5, so that the bronchial asthma disease is effectively treated.

Description

technical field [0001] The invention relates to the technical field of iris flavin A, and relates to the application of iris flavin A in the preparation of medicines for preventing and treating bronchial asthma. Background technique [0002] Asthma is an inflammation-related disease that seriously threatens people's physical and mental health. Excessive local inflammation, immune disturbance and airway hyperresponsiveness are the main pathological features. Anti-inflammatory treatment of general asthma is its main treatment principle, and glucocorticoid is an important treatment method. However, the long-term use of such drugs will lead to drug resistance, which will seriously affect the quality of life of patients in the later stage. Contents of the invention [0003] The present invention provides an application of iris flavin A in the preparation of drugs for preventing and treating bronchial asthma, which overcomes the above-mentioned deficiencies in the prior art, a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/352A61P11/06
CPCA61K31/352A61P11/06
Inventor 买买提江·阿布都瓦克乃比江·麦图荪吾尼切木·吐拉克
Owner 新疆维吾尔医学专科学校
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