Fibronectin freeze-dried powder preparation and preparation method thereof

A technology of fibronectin and freeze-dried powder, which is applied to skin care preparations, pharmaceutical formulations, cosmetic preparations, etc. Good morphological structure, maintaining good cell morphological structure, and promoting cell movement

Active Publication Date: 2021-11-02
湖南本美生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the prior art, there are few studies on lyophilized powder containing fibronectin and related preparations, and most of them have not further analyzed its effect on cell activity and other effects such as convenient water content during application.

Method used

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  • Fibronectin freeze-dried powder preparation and preparation method thereof
  • Fibronectin freeze-dried powder preparation and preparation method thereof
  • Fibronectin freeze-dried powder preparation and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0034] A fibronectin freeze-dried powder preparation, including fibronectin freeze-dried powder and enzyme liquid;

[0035] Among them, the fibronectin freeze-dried powder is calculated in parts by weight, including: 28 parts of fibronectin, 4 parts of mannitol, 1.5 parts of brown algae extract, 2 parts of Phaeodactylum tricornutum extract, 0.6 part of pH regulator, 0.2 parts buffer and 63.7 parts water.

[0036] The enzyme solution comprises, in parts by weight, 0.5 parts of carboxymethyl chitosan, 3 parts of peony extract, 6 parts of chlorella extract, 4 parts of moisturizing agent, 0.15 part of chelating agent and 86.35 parts of water.

[0037] The preparation method of above-mentioned fibronectin freeze-dried powder comprises the following steps:

[0038] (1) Disinfect and clean the mixing pot, then add the prepared raw materials into fibronectin, buffer and water in sequence, stir evenly and disperse completely, add brown algae extract and Phaeodactylum tricornutum extra...

Embodiment 2

[0053] A fibronectin freeze-dried powder preparation, including fibronectin freeze-dried powder and enzyme liquid;

[0054] Among them, the fibronectin freeze-dried powder includes: 36 parts of fibronectin, 7 parts of mannitol, 0.5 part of brown algae extract, 0.5 part of Phaeodactylum tricornutum extract, 0.3 part of pH regulator, 0.1 part of buffer and 55.6 parts water.

[0055] The enzyme solution comprises, in parts by weight, 1.5 parts of carboxymethyl chitosan, 7 parts of peony extract, 8.5 parts of chlorella extract, 2 parts of moisturizing agent, 0.1 part of chelating agent and 80.9 parts of water.

[0056] The preparation method of above-mentioned fibronectin freeze-dried powder comprises the following steps:

[0057] (1) Disinfect and clean the mixing pot, then add the prepared raw materials into fibronectin, buffer and water in sequence, stir evenly and disperse completely, add brown algae extract and Phaeodactylum tricornutum extract, stir evenly to ensure complet...

Embodiment 3

[0069] A fibronectin freeze-dried powder preparation, including fibronectin freeze-dried powder and enzyme liquid;

[0070] Among them, the fibronectin freeze-dried powder includes: 34 parts of fibronectin, 6 parts of mannitol, 1 part of brown algae extract, 1 part of Phaeodactylum tricornutum extract, 0.44 parts of pH regulator, 0.13 parts buffer and 57.43 parts water.

[0071] The enzyme solution comprises, in parts by weight, 1 part of carboxymethyl chitosan, 5 parts of peony extract, 7 parts of chlorella extract, 3 parts of moisturizing agent, 0.1 part of chelating agent and 83.9 parts of water.

[0072] The preparation method of above-mentioned fibronectin freeze-dried powder comprises the following steps:

[0073] (1) Disinfect and clean the mixing pot, then add the prepared raw materials into fibronectin, buffer and water in sequence, stir evenly and disperse completely, add brown algae extract and Phaeodactylum tricornutum extract, stir evenly to ensure complete disso...

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Abstract

The invention provides a fibronectin freeze-dried powder preparation and a preparation method thereof, and relates to the technical field of cosmetics. The fibronectin freeze-dried powder preparation comprises fibronectin freeze-dried powder and an enzyme solution; wherein the fibronectin freeze-dried powder comprises fibronectin, mannitol, a brown algae extract, a phaeodactylum tricornutum extract, a pH regulator, a buffering agent and water. The freeze-dried powder preparation has high nutrition and high activity and can be used for intensively repairing, the skin absorption efficiency can reach more than 20 times by adopting a biological transdermal absorption technology, and the water content and the cell viability of the skin can be effectively improved.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a fibronectin freeze-dried powder preparation and a preparation method thereof. Background technique [0002] Freeze-dried powder is a sterile powder injection made by freezing the medicinal liquid into a solid state in a sterile environment, sublimating and drying the water in a vacuum, because it can well retain the active ingredients and has deep penetration and fast absorption. Therefore, it is widely used in the fields of medicine and cosmetics. In the past, EGF was often added to freeze-dried powder due to its strong repairing ability. However, after EGF cannot be used as a cosmetic raw material, how to find a suitable substitute has become a more concerned issue at present. Fibronectin is a macromolecular outer membrane protein present on the surface of various animal cells. It is the main non-collagenous glycoprotein in the extracellular matrix and basement membrane. I...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/9794A61K8/34A61K8/64A61K8/73A61K8/9711A61K8/9722A61Q19/00
CPCA61K8/9711A61K8/64A61K8/345A61K8/9722A61K8/9789A61K8/9794A61K8/735A61Q19/00A61K2800/5922A61K2800/84
Inventor 简经红
Owner 湖南本美生物科技有限公司
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