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Skin composition

A composition and skin technology, applied in the direction of drug combinations, skin diseases, skin care preparations, etc., can solve problems such as irritation and difficulty in using skin film-forming compositions

Pending Publication Date: 2021-09-10
MARUHO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in order to improve quick-drying properties, many of them contain low-level monohydric alcohols such as ethanol and isopropanol, which may cause irritation when applied.
Similarly, in the case of hand eczema, sebum deficiency, atopic dermatitis, etc., where the skin barrier function is reduced, the affected area tends to spread to a wider area, and it is difficult to use low-level monoalcohols that cause skin dryness and irritation. film-forming composition

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example 1 and 2

[0084] Weigh ethyl acrylate-methyl methacrylate-methacryloxyethyltrimethylammonium chloride copolymer (composition ratio 1:2:0.2) and purified water, add ethylene glycol salicylate, stir to uniform.

preparation example 3～8

[0086]Weigh ethyl acrylate-methyl methacrylate-methacryloxyethyltrimethylammonium chloride copolymer (composition ratio 1:2:0.1) and purified water, add diethyl sebacate, stir until uniform. In addition, about the formulation example 3, the same operation was performed without adding diethyl sebacate.

preparation example 9～15

[0088] Weigh ethyl acrylate-methyl methacrylate-methacryloxyethyltrimethylammonium chloride copolymer (composition ratio 1:2:0.1), medium-chain fatty acid triglycerides and purified water, add citric acid triethyl ester, triacetin, diisopropyl adipate, diisopropyl sebacate, diethyl sebacate, ethylene glycol salicylate, or phenoxyethanol and stir until homogeneous. It was put into a pressure-resistant container and pressed into DME to obtain an aerosol.

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PUM

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Abstract

The present invention addresses the problem of providing a coating-forming-type skin composition (coating-type skin protective agent, coating-type skin topical agent, or the like) that does not contain a lower monovalent alcohol such as ethanol and isopropanol, that has excellent quick-drying ability and water resistance, and that is less sticky and provides excellent sensation when being used. The present invention pertains to a coating-forming-type skin composition characterized by containing a specific acrylic polymer, a plasticizing agent, and water, but substantially not containing a lower monovalent alcohol such as ethanol and isopropanol. The composition according to the present invention is extremely useful in the therapy of chronic skin diseases, etc., represented by hand eczema, atopic dermatitis, or the like (i.e., skin diseases with reduced skin barrier function).

Description

technical field [0001] The present invention relates to a film-forming composition, and more specifically, to a film-forming skin protectant and a film-forming external preparation for skin. Background technique [0002] Liquid band-aids that form a thin film are effective for symptoms of decreased skin barrier function (barbs, abrasions, cracks, etc.), and are marketed for the purpose of protecting the skin from work in contact with water. However, in order to improve quick-drying properties, many low-level monohydric alcohols such as ethanol and isopropanol are contained, which causes irritation when applied. Similarly, in the case of hand eczema, sebum deficiency, atopic dermatitis, etc., where the skin barrier function is reduced, the affected area tends to spread to a wider area, and it is difficult to use low-level monoalcohols that cause skin dryness and irritation. film-forming compositions. Patients and medical personnel wish to develop a film-forming composition ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P17/00A61K9/08A61K9/12A61K47/02A61K47/14A61K47/32
CPCA61P17/00A61K47/32A61K8/34A61K8/37A61K47/14A61K9/7015A61K47/10A61K9/0014A61K47/06A61K8/8147A61K8/31A61K8/553A61K8/29A61K8/25A61K47/02A61K9/12A61K8/02A61K8/368A61Q19/00A61K2800/30A61L26/0004A61L26/0014A61L26/0071
Inventor 中村文子崎山祥纪L·哈夫西大塚直哉
Owner MARUHO
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