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SNP molecular marker influencing birth weight of alpine merino and application thereof

A Merino sheep and molecular marker technology, applied in the field of molecular genetics, can solve the problems of long breeding cycle and slow genetic progress, and achieve the effects of high accuracy, low cost and fast detection speed

Active Publication Date: 2021-08-17
LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional breeding methods mostly use traditional phenotypic breeding techniques, that is, to infer parental productivity based on offspring phenotype information, long breeding cycle, and slow genetic progress

Method used

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  • SNP molecular marker influencing birth weight of alpine merino and application thereof
  • SNP molecular marker influencing birth weight of alpine merino and application thereof
  • SNP molecular marker influencing birth weight of alpine merino and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1 Correlation Between Different Genotypes and Birth Weight of Alpine Merino Sheep

[0033] 1. Sample Collection

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PUM

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Abstract

The invention relates to the technical field of gene engineering, in particular to an SNP molecular marker influencing birth weight of alpine merino and application of the SNP molecular marker. The SNP molecular marker is located at the 18805219th nucleotide site C > G mutation on the 14th chromosome of the international sheep reference genome Oar_v4.0 version. The invention also relates to a specific primer pair for detecting the SNP molecular marker by using an SNaPshot technology, a kit containing the specific primer pair and a nucleotide polymorphism detection method. Compared with a traditional detection method, the technology has the characteristics of high accuracy, high detection speed, low cost, easiness in result judgment and the like. The SNP locus detection is used for carrying out early selection of the birth weight character of the alpine merino sheep, shortening the breeding period and accelerating the breeding process, an early selection technology of the birth weight character of the alpine merino sheep is established, the breeding time of excellent characters of the birth weight character of the alpine merino sheep is shortened, the breeding cost is reduced, and the application value is very high.

Description

technical field [0001] The invention belongs to the technical field of molecular genetics, and in particular relates to a SNP molecular marker affecting the birth weight of Alpine Merino sheep and its application. Background technique [0002] For breeding stock, fecundity is productivity, and reproductive performance is directly related to the economic effect of animal husbandry industry. The reproductive performance of sheep mainly includes indicators such as the total number of lambs born, the number of live lambs born, newborn weight, newborn litter weight, and weaned litter weight. The birth weight of sheep is the birth weight of sheep, which is an important quantitative trait to measure sheep, and affects the growth and development, production performance and carcass grade of sheep. Birth weight was also positively correlated with weaning survival rate, weaning weight and slaughter weight, and negatively correlated with slaughter age. Moreover, sheep with low birth w...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12Q1/6888C12N15/11
CPCC12Q1/6888C12Q2600/124C12Q2600/156C12Q2600/172
Inventor 郭婷婷袁超卢曾奎杨博辉岳耀敬牛春娥刘建斌李建烨
Owner LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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