Application of figs and whey thereof in preparation of drugs for inhibiting melanoma and tumor vascular

Abstract

The invention provides application of figs and whey thereof in preparation of drugs for inhibiting melanoma and tumor vascular, and relates to the field of traditional Chinese medicines. The application of the figs and the whey thereof in preparing the drugs for inhibiting melanoma and tumor vascular comprises the following steps: step 1, extracting the figs; and step 2, preparing the fig whey. Analysis on toxicity, proliferation, migration, invasion and apoptosis of melanoma cells by the figs and the fig whey shows that the figs and the fig whey have obvious inhibition effects on proliferation, migration and invasion of melanoma and promote cell apoptosis, the fig water extract and the ethyl acetate part product are non-toxic to the cells, the fig water extract and the product of an ethyl acetate part have no toxic effect on the cells, the product of a precipitation part is toxic to the cells, and analysis on the survival rate of the tumor vascular cells shows that the fig water extract and the product of the ethyl acetate part both can inhibit invasion of Huvec cells, and can have the capacity of reducing angiogenesis in a dose-dependent manner.

Description

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AI Technical Summary

Benefits of technology

This patented technology helps prevent or reduce cell division during skin cancer development through promoter activity for growth/movement (cell movement) on melanocytes. It also suggests studying how these molecules affect different aspects of this process such as reducing inflammations caused by chemotherapy drugs or enhancing drug delivery into specific areas within the body's vasculature.

Problems solved by technology

This patented technical problem addressed in this patent describes how we could find ways to prevent melanomas that were previously difficult to treat because they had severe symptoms caused them to spread through other areas like bone marrow during childhood.

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