Application of combination of hydrolyzed yeast protein and chicory root extract in preparation of hair growing and nourishing products

A technology of chicory root extract and hydrolyzed yeast protein, which is applied to cosmetic preparations, cosmetic preparations, medical preparations containing active ingredients, etc., can solve side effects, allergic reactions to finasteride, and it is difficult to play an effective role and other problems, to achieve the effect of promoting hair growth and promoting blood circulation

Active Publication Date: 2021-08-10
宁波见睿新材料有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned hair growth products can promote hair regeneration, but they also have some side effects, which affect their widespread use. For example, minoxidil can cause hypertrichosis and contact pigmentation dermatitis, and finasteride can also cause allergies reaction
[0007] In addition, the scalp is composed of four cell layers, the stratum corneum, the granular layer, the stratum corneum, and the base layer, and contains a large number of hair follicles, sebaceous glands, and sweat glands. If the effective ingredients are attached to the scalp for a short time, it is not easy to absorb into the scalp. difficult to function effectively

Method used

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  • Application of combination of hydrolyzed yeast protein and chicory root extract in preparation of hair growing and nourishing products
  • Application of combination of hydrolyzed yeast protein and chicory root extract in preparation of hair growing and nourishing products
  • Application of combination of hydrolyzed yeast protein and chicory root extract in preparation of hair growing and nourishing products

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] To prepare chicory root extract:

[0059] Put 500g of chicory roots in an oven, dry them at 60°C for two hours, slice them into slices (about 0.5cm thick), pulverize them in a traditional Chinese medicine grinder for 15 minutes, and sieve them to obtain chicory root powder, about 100 meshes. 480g; Take 50g of chicory root powder with an electronic balance, wrap the powder in a degreased filter paper bag, put it into an extraction tube, extract with Soxhlet extraction, add sherwood oil (about 300mL) to the volume of the extraction bottle in the extraction bottle In two-thirds of the place, in a water bath, heat the extraction bottle at 60°C, with a siphon speed of about 20 times per hour, reflux for 6 hours, and a reflux temperature of 60°C, filter to remove fat-soluble impurities, and discard the filtrate; press 1:10 ( Weight ratio) Add distilled water to the filter residue, heat the water bath to 45°C in an ultrasonic water bath, ultrasonic for 40 minutes, power 160W, ...

Embodiment 2

[0061] Testing the histological effects of chicory root extract on the back skin of guinea pigs:

[0062] 2.1 Prepare respectively 50 mg / mL and 20 mg / mL aqueous solutions of the chicory root extract prepared in Example 1 as test solutions, control group: distilled water.

[0063] 2.2 Guinea pig model for testing: 15 guinea pigs, half male and half female, weighing between 250-300g, divided into 3 groups (smear blank solution (the composition of the blank solution is water), chicory root extract 50mg / mL solution and Chicory root extract 20mg / mL solution), 5 rats in each group.

[0064] 2.3 Test method:

[0065] One day before the experiment, depilate the back of the guinea pigs in each group with depilatory cream. The exposed skin area is 10cm 2 ;Apply the corresponding solution once a day, 0.5mL each time, for 20 consecutive days. The skin changes and hair growth on the back of the guinea pigs were observed daily, and the hair length of the guinea pigs in the experimental ...

Embodiment 3

[0074] Testing the effect of hydrolyzed yeast protein combined with chicory root extract to promote hair growth in guinea pigs

[0075] 3.1 Use the chicory root extract prepared in Example 1 and the hydrolyzed yeast protein to configure the following five aqueous solutions as test solutions: the aqueous solution of the chicory root extract and hydrolyzed yeast protein (1:2, w / w) mixture (concentration is 50 mg / w) mL), the aqueous solution of the mixture of chicory root extract and hydrolyzed yeast protein (1:1, w / w) (concentration is 50mg / mL), the mixture of chicory root extract and hydrolyzed yeast protein (2:1, w / w) Aqueous solution (concentration: 50mg / mL), aqueous solution of chicory root extract (concentration: 50mg / mL), aqueous solution of hydrolyzed yeast protein (concentration: 50mg / mL).

[0076] Blank control group: distilled water.

[0077] 3.2 Guinea pig model for testing: 30 guinea pigs, half male and half male, divided into 6 groups, 5 guinea pigs in each group, ...

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Abstract

The invention provides an application of combination of hydrolyzed yeast protein and a chicory root extract in preparation of hair growing and nourishing products. The combination of the hydrolyzed yeast protein and the chicory root extract can significantly and effectively improve and enhance the hair follicle structure, nourish and strengthen the hair roots, and improve the hair growth cycle, thereby promoting the hair growth.

Description

technical field [0001] The present invention relates to the use of hydrolyzed yeast protein combined with chicory root extract in the preparation of hair growth and hair growth products. Background technique [0002] Hair loss and hair loss are considered signs of aging. Various reasons lead to brittle hair up to hair loss, such as internal factors (stress, genetic factors) and external factors such as environmental factors (sun, wind, pollution), physical factors (shampooing, drying, combing, etc...) and chemical factors (hair dyeing, bleaching). [0003] Hair growth and regeneration is primarily dependent on the activity of the hair follicle and the active state of its matrix. The hair follicle is a complex independent skin appendage, and the organization and strength of the hair shaft and hair depend on the activity and health of the hair follicle. The growth cycle of the hair follicle (see figure 1 ) includes three stages of the cycle, namely anagen, catagen and telo...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/64A61Q5/00A61Q5/12A61Q7/00
CPCA61K8/9789A61K8/64A61Q7/00A61Q5/12A61Q5/00A61K2800/82A61K2800/84
Inventor 李明霞冯冲李延博贾正浩
Owner 宁波见睿新材料有限公司
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