Oral care compositions comprising a polyvinyl capralactam-polyvinyl acetate-polyethylene glycol graft copolymer, and methods for the same
一种聚乙酸乙烯酯、聚乙二醇接枝的技术,应用在护理口腔、含有效成分的医用配制品、医药配方等方向,能够解决不能提供均质或异质的凝胶等问题
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[0096] A structure builder, polyvinylcaprolactam-polyvinyl acetate-polyethylene glycol graft copolymer (PCA-PVA-PEG) was evaluated Efficacy for the preparation of oral care compositions in gel form. Generally, about 30 to about 50% by weight of PCA-PVA-PEG and about 50 to about 70% by weight of the different carrier (ie, liquid carrier) are combined with each other via speed mixing. After mixing, each gel mixture was brought to room temperature and evaluated. The results of the study are summarized in Table 1.
[0097] Table 1
[0098]
[0099] As shown in Table 1, PCA-PVA-PEG was able to form stable homogeneous gels with water, propylene glycol, polyethylene glycol 600, dimethyl isosorbide and triacetin. Therefore, PCA-PVA-PEG was able to form a well-structured gel matrix with water, propylene glycol, polyethylene glycol 600, dimethyl isosorbide, and triacetin. As further shown in Table 1, PCA-PVA-PEG was able to form heterogeneous gels with glycerol, sorbitol and plu...
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