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Skin wound repairing composition containing plant extracts and preparation method thereof

A technology of plant extracts and skin wounds, applied in the field of skin wound repair compositions containing plant extracts and its preparation, can solve problems such as skin scars, limited treatment methods, and high risk of wound healing and infection in patients, and promote cell proliferation Effects of regeneration, promotion of blood circulation, and reduction of scars

Pending Publication Date: 2021-07-23
THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Topical antibacterial medication is the main way to treat burns and scalds. However, in addition to antibacterial treatment, third-degree burns and scalds often require skin grafting when the area is large or the damage is deep. Generally, skin grafting includes autologous skin grafting and allogeneic skin grafting. , autologous skin transplantation needs to take the patient's own healthy skin for cultivation and then transplant it to the patient's wound. However, patients with severe burns and scalds have large wounds, and autologous skin often cannot meet the needs of transplantation, and taking autologous skin will cause secondary damage and increase infection. probability; allogeneic skin transplantation usually uses artificial skin, such as pigskin after decellularization for skin transplantation, but the development of artificial skin technology at home and abroad is still immature, the performance is unstable, immune rejection is prone to occur, and the price is high. People can't afford the high medical bills
[0004] At present, there are limited treatment methods for second-degree and third-degree burn patients at home and abroad, mainly through antibacterial and vital sign support therapy. In severe cases, skin grafting treatment is used. The risk of wound healing and infection is high, especially the local topical drugs are very limited, which is difficult to meet severe burns and scalds. According to the needs of patients, severe scars and abnormal pigmentation are common in the late stage of second and third degree burns

Method used

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  • Skin wound repairing composition containing plant extracts and preparation method thereof
  • Skin wound repairing composition containing plant extracts and preparation method thereof
  • Skin wound repairing composition containing plant extracts and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] The present embodiment provides a skin wound repair composition, which consists of the following components in parts by weight: 15 parts of pumpkin-aloe compound extract and 0.05 part of superoxide dismutase; the pumpkin-aloe compound extract consists of A blend of pumpkin and aloe vera is sealed and fermented. In some embodiments, the pumpkin-aloe complex extract has 10 parts, 11 parts, 12 parts, 13 parts or 14 parts by weight. In some embodiments, the weight part of the superoxide dismutase is 0.01 part, 0.02 part, 0.03 part or 0.04 part. In some embodiments, the ratio of pumpkin and aloe used in the pumpkin-aloe composite extract is 7:4. After repeated experiments, the effect is the best when the ratio of pumpkin and aloe vera is 7:4.

Embodiment 2

[0042] This embodiment provides a skin wound repair composition, which consists of the following components in parts by weight: 10 parts of pumpkin-aloe compound extract, 0.05 part of superoxide dismutase and 0.5 part of Panax notoginseng injection. In some embodiments, the weight part of the Sanqi injection is 0.5 part, 0.6 part, 0.7 part, 0.8 part, 0.9 part or 1 part. The Sanqi injection has the effect of promoting blood circulation and removing blood stasis. The present invention has been verified through a large number of experiments. Adding 0.5-1 parts of Sanqi injection can prevent dermal vascular embolism, prevent scar hyperplasia, and relieve pain. On the other hand, the present invention Continuous use of the pumpkin-aloe compound extract can keep the patient's skin moist for a long time. After compounding with Sanqi injection, Sanqi injection can be fully absorbed by the skin, and the damaged microvessels of the dermis can be quickly restored, shortening the skin repa...

Embodiment 3

[0044] This embodiment provides a skin wound repair composition, which consists of the following components in parts by weight: 10 parts of pumpkin-aloe complex extract, 0.05 parts of superoxide dismutase and 60 parts of sterile water. In some embodiments, the parts by weight of the sterile water are 65 parts, 68 parts, 70 parts, 75 parts, 78 parts, 80 parts, 82 parts, 85 parts, 87 parts, 88 parts, 89 parts or 90 parts share. After the pumpkin-aloe complex extract of the present invention is diluted with sterile water, it is made into a spray and used, which is more convenient to use.

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Abstract

The invention provides a skin wound repairing composition containing plant extracts, which is prepared from the following components in parts by weight: 10-15 parts of a pumpkin-aloe compound extract, 0.01-0.1 part of superoxide dismutase and 0-90 parts of auxiliary components, wherein the pumpkin-aloe compound extract is prepared by sealing and fermenting a mixture of pumpkins and aloe. The skin wound repairing composition provided by the invention has a remarkable effect in the aspect of treating second-degree and third-degree skin burns and scalds.

Description

technical field [0001] The invention belongs to the technical field of skin treatment medicines, and in particular relates to a skin wound repairing composition containing plant extracts and a preparation method thereof. Background technique [0002] Burns generally refer to body surface tissue damage caused by heat such as boiling liquid (water, oil, soup), hot metal (liquid or solid), flame, steam, and high-temperature gas, mainly skin damage. The main manifestations are redness, swelling, blisters, peeling, pain, etc. on the skin of the burnt area. According to the depth of burns, it is generally divided into three degrees, namely first-degree burns, second-degree burns and third-degree burns. First-degree burns only hurt the epidermis. The injured skin is red, swollen, and feels burning pain, but no blisters appear. Second-degree burns refer to injury to the dermis, local redness and swelling, fever, unbearable pain, and obvious blisters; third-degree burns refer to ful...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/44A61K9/70A61L15/18A61L15/28A61L15/32A61L15/38A61L15/40A61L15/44A61L15/46A61P17/02A61P29/00A61P31/02A61K31/702A61K31/728A61K38/39
CPCA61K36/42A61K36/896A61K36/886A61K38/446C12Y115/01001A61K36/258A61P17/02A61P29/00A61P31/02A61K31/702A61K38/39A61K31/728A61K9/70A61L15/40A61L15/28A61L15/325A61L15/18A61L15/44A61L15/46A61L15/38A61K2236/19A61L2300/404A61L2300/30A61L2300/41A61L2300/412A61L2300/254A61L2300/252A61K2300/00
Inventor 韩丹周艳
Owner THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV
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