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Plant anti-allergy soothing composition as well as preparation method and application thereof

A composition and plant technology, applied in the directions of drug combinations, plant raw materials, medical raw materials derived from angiosperms, etc., can solve problems such as affecting skin health and affecting the process of inflammatory response, and achieve excellent anti-inflammatory, low production cost, The effect of easy availability of resources

Active Publication Date: 2021-07-23
上海内见慧生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is evidence that NF-kB can also induce gene expression of various cytokines such as TNF-α, adhesion molecules, chemokines and C-reactive protein, thereby affecting the process of inflammatory response and affecting the health of the skin

Method used

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  • Plant anti-allergy soothing composition as well as preparation method and application thereof
  • Plant anti-allergy soothing composition as well as preparation method and application thereof
  • Plant anti-allergy soothing composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] This example provides a plant anti-allergic soothing composition, including the following raw materials: 15g of alpine edelweiss, 80g of rehmannia glutinosa, and 5g of matsutake fungus.

[0041] The plant anti-allergic soothing composition in this embodiment is prepared by the following method:

[0042] S1. Accurately weigh 15g of alpine edelweiss, 80g of rehmannia glutinosa, and 5g of matsutake fungus, and mix alpine edelweiss and rehmannia glutinosa evenly to obtain a mixture;

[0043] S2. Add 285g of water to the mixture, mix evenly, then pack into solid fermentation bags, sterilize and cook for 2 hours, and cool to normal temperature;

[0044] S3. Inoculate 5 g of matsutake mushroom strains weighed in step S1 into a fixed fermentation bag, and perform solid-state fermentation at an ambient temperature of 20° C. for 3 days;

[0045] S4. Take out the solid fermentation product and add 1200g of 70% ethanol aqueous solution, reflux extraction at 65°C for 2h, remove the...

Embodiment 2

[0049] This example provides a plant anti-allergic soothing composition, which includes the following raw materials: 30g of Hedyotis diffusa, 60g of Andrographis paniculata, and 10g of matsutake fungus.

[0050] The plant anti-allergic soothing composition in this embodiment is prepared by the following method:

[0051] S1. Accurately weigh 30g of Hedyotis diffusa, 60g of Andrographis paniculata, 10g of matsutake strain, mix Hedyotis diffusa and Andrographis paniculata evenly to obtain a mixture;

[0052] S2. Add 450 g of water to the mixture, mix evenly, then pack into solid fermentation bags, sterilize and cook for 6 hours, and cool to normal temperature;

[0053] S3. Inoculate 10 g of matsutake mushroom strains weighed in step S1 into a fixed fermentation bag, and perform solid-state fermentation for 10 days at an ambient temperature of 40° C.;

[0054] S4. Take out the solid fermentation product and add 2500g of water, reflux and extract at 95°C for 2h, remove the filter ...

Embodiment 3

[0058] This example provides a plant anti-allergic soothing composition, including the following raw materials: 20g of alpine edelweiss, 70g of rehmannia glutinosa, and 10g of matsutake fungus.

[0059] The plant anti-allergic soothing composition in this embodiment is prepared by the following method:

[0060] S1. Accurately weigh 20g of alpine edelweiss, 70g of rehmannia glutinosa, and 10g of Tricholoma matsutake strains, and mix the alpine edelweiss and rehmannia glutinosa evenly to obtain a mixture;

[0061] S2. Add 360g of water to the mixture, mix evenly, then pack into solid fermentation bags, sterilize and cook for 5 hours, and cool to normal temperature;

[0062] S3. Inoculate 10 g of pine mushroom strains weighed in step S1 into a fixed fermentation bag, and conduct solid-state fermentation for 7 days at an ambient temperature of 30° C.;

[0063] S4, take out the solid fermented product, add 2500g of 50% ethanol aqueous solution, reflux and extract at 80°C for 3h, r...

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Abstract

The invention discloses a plant anti-allergy soothing composition as well as a preparation method and application thereof. The plant anti-allergy soothing composition comprises the following raw materials: a plant component A, a plant component B and a tricholoma matsutake strain; wherein the plant component A is leontopodium alpinum or oldenlandia diffusa, and the plant component B is radix rehmanniae or andrographis paniculata. The plant anti-allergy soothing composition disclosed by the invention has excellent anti-inflammatory, anti-allergy and soothing effects, is mild and non-irritant, is suitable for long-term use, and overcomes the defects that existing anti-allergy and soothing products are mostly hormone products, which have strong dependence and large side effects. The plant anti-allergy soothing composition is obtained by compounding the plant component A, the plant component B and the tricholoma matsutake strain, on one hand, anti-allergy and soothing effects are achieved through the principle of inhibiting release of histamine and increasing tolerance of skin to histamine, and on the other hand, anti-inflammatory, anti-allergy and soothing effects are achieved by inhibiting expression of inflammatory factors.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a plant anti-allergy soothing composition and its preparation method and application. Background technique [0002] With the development of society, people's living standards have been greatly improved. However, with the increasing social pressure from work and life and the increasing environmental pollution, skin allergies, itching, dermatitis, etc. Various symptoms. Therefore, there is an increasing demand for products with natural anti-allergic, anti-inflammatory and soothing effects. At present, one of the main factors leading to skin diseases in people is: exogenous or endogenous substances stimulate mast cells, and then produce histamine to act on nerve endings, resulting in erythema, papules, itching, pain, allergies and other symptoms. Therefore, only by inhibiting the release of histamine and increasing the skin's tolerance to histamin...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61K36/748A61K36/28A61P17/00A61P37/08A61P29/00A61P17/04
CPCA61K36/28A61K36/748A61K36/804A61K36/19A61K36/07A61K9/0014A61P17/00A61P37/08A61P29/00A61P17/04A61K2236/19A61K2236/331A61K2236/333A61K2236/51A61K2236/53A61K2300/00
Inventor 王勇代丽华
Owner 上海内见慧生物科技有限公司
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