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Pharmaceutical composition for reducing blood fat

A composition and blood lipid-lowering technology, which can be used in drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., and can solve problems such as high prices

Pending Publication Date: 2021-07-20
深圳市长卿医学研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Proprotein convertase subtilisin 9 (PCSK9) inhibitors such as evolocumab require subcutaneous injections and are expensive

Method used

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  • Pharmaceutical composition for reducing blood fat
  • Pharmaceutical composition for reducing blood fat
  • Pharmaceutical composition for reducing blood fat

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 13

[0042] Example 13: We have designed the following experiments, mainly through the detection of TC, TG, LDL-blood lipids and endothelial function indicators of experimental animals, to investigate the efficacy of the composition of the present invention, and the experiment proves that the composition of the present invention has synergistic lipid-lowering and endothelial Protection against atherosclerosis.

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Abstract

The invention provides a pharmaceutical composition for reducing blood fat. The pharmaceutical composition is prepared from Bempedoic acid, fibrate lipid-lowering drugs, folic acid and a proper amount of auxiliary materials. The pharmaceutical composition provided by the invention provides an effective medicine for hyperlipidemia patients, and the three medicines are combined for use and have a synergistic effect. In addition, the pharmaceutical composition can be conveniently taken by a patient, the compliance is improved, and the medical cost is reduced.

Description

technical field [0001] The invention relates to a pharmaceutical composition, more precisely, the invention relates to a pharmaceutical composition with better lipid-lowering effect. belongs to the field of pharmacy. Background technique [0002] With the change of diet structure and lifestyle, human diseases are also constantly evolving. In recent years, people's awareness of health care is relatively weak, and the incidence of hyperlipidemia, coronary heart disease and related diseases is increasing year by year. Dyslipidemia is one of the important risk factors for cardiovascular disease. Hyperlipidemia is an independent risk factor for coronary heart disease. Dyslipidemia plays a major role in the occurrence, development and deterioration of atherosclerosis. It is related to the onset of heart disease, the stability or progression of lesions, which seriously threatens the life and quality of life of patients. There are many blood lipid testing items clinically, and the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K45/06A61K31/191A61K31/216A61K31/519A61P3/06
CPCA61K45/06A61K31/191A61K31/216A61K31/519A61P3/06A61K2300/00
Inventor 于多陈光亮王滨燕
Owner 深圳市长卿医学研究院
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