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Method and system for automatically analyzing pathogen types

An automatic analysis, pathogen technology, applied in the information field, to achieve the effect of reducing the amount of calculation and good data compatibility

Pending Publication Date: 2021-07-09
北京源生康泰基因科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The present invention proposes a method and system for automatic analysis of pathogen types to solve the problem of how to quickly and accurately determine the type of pathogens in samples to be tested based on three-generation sequencing data

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  • Method and system for automatically analyzing pathogen types
  • Method and system for automatically analyzing pathogen types
  • Method and system for automatically analyzing pathogen types

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Embodiment Construction

[0056] Exemplary embodiments of the present invention will now be described with reference to the drawings; however, the present invention may be embodied in many different forms and are not limited to the embodiments described herein, which are provided for the purpose of exhaustively and completely disclosing the present invention. invention and fully convey the scope of the invention to those skilled in the art. The terms used in the exemplary embodiments shown in the drawings do not limit the present invention. In the figures, the same units / elements are given the same reference numerals.

[0057] Unless otherwise specified, the terms (including scientific and technical terms) used herein have the commonly understood meanings to those skilled in the art. In addition, it can be understood that terms defined by commonly used dictionaries should be understood to have consistent meanings in the context of their related fields, and should not be understood as idealized or over...

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Abstract

The invention discloses a method and system for automatically analyzing pathogen types. The and comprises the following steps that: pathogen types of first sequencing read data of different data types of a to-be-detected sample are preliminarily judged through two different algorithms, and second sequencing read data are selected; then comparison verification and screening are performed on the identified second sequencing read data of the different pathogen types and corresponding pathogen reference sequences, and therefore, pathogen types existing in the to-be-detected sample can be determined. According to the method, long read length data generated based on a third-generation sequencing technology can be effectively processed, the calculation amount of accurate comparison is reduced, accurate analysis and report generation of typical third-generation metagenome or metatranscriptome data within 30 minutes can be achieved, and the requirement for rapid pathogen detection and analysis is met; and meanwhile, the method can be used for analyzing short read length data obtained by next-generation sequencing, and has relatively good data compatibility.

Description

technical field [0001] The present invention relates to the field of information technology, and more particularly, relates to a method and system for automatic analysis of pathogen types. Background technique [0002] The main technology and implementation plan of the pathogen identification method based on high-throughput sequencing data is to use a high-throughput sequencer to measure the nucleic acid sequence in the sample through experimental steps such as sample pretreatment, nucleic acid extraction, and sequencing library construction. After obtaining the nucleic acid sequence data produced by the sequencer, use sequence comparison software to compare and analyze these sequences with the pathogen sequence database, and use certain comparison result filter conditions to screen to obtain reliable results, and then calculate the nucleic acid sequence of the sample The number of sequences belonging to pathogens in the data and the proportion of all sequences, etc., finall...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16B30/10G16B20/30
CPCG16B30/10G16B20/30Y02A90/10
Inventor 杜鹏程余乐刘树青
Owner 北京源生康泰基因科技有限公司
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