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A kind of functional dressing and preparation method thereof

A functional, volatile organic technology, applied in adhesive dressings, non-adhesive dressings, dressings, etc., can solve the problems of accelerated micro-current stimulation, inconvenient use, etc., and achieve improved spinning efficiency, convenient use, and good biocompatibility Effect

Active Publication Date: 2022-07-08
ZHONGHAO CHENGUANG RES INST OF CHEMICALINDUSTRY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it is the same as the Chinese patent application CN110090316A, which stimulates wound healing through the micro-current formed by the electret. Both of them need to use constant voltage corona charging. After discharging, they need to be recharged to accelerate the micro-current stimulation function, which is inconvenient to use. Requires special charging equipment

Method used

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  • A kind of functional dressing and preparation method thereof
  • A kind of functional dressing and preparation method thereof
  • A kind of functional dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Dissolve PVDF powder (molecular weight 550,000) in N,N-dimethylformamide, stir and dissolve in an oil bath at 50°C to obtain a uniform and transparent solution (the first spinning solution) with a mass concentration of 25%, extract 5mL with a 10mL syringe The above spinning solution was electrospun, and the fiber filaments were received into a film-like structure to obtain a fiber film with a thickness of 0.08 mm. Electrospinning parameters were: spinning voltage 10 kV, spinning advancing speed 2 mL / h, receiving distance 20 cm, inner diameter of spinning needle 0.8 mm, spinning temperature 25 °C, and receiving time 2 h. Liquid silicone resin for the prepared fiber membrane (80 parts of 1053 silicone resin of Zhonghao Chenguang Chemical Research Institute Co., Ltd. + 18 parts of GY209-3 hydroxy silicone oil of Zhonghao Chenguang Chemical Research Institute Co., Ltd. + 2 parts of Shandong Qufu Chemical Co., Ltd. KH550, The viscosity of coating -4 cups is 68s, and the Shor...

Embodiment 2

[0052] Dissolve PDMS (Jiangxi Lanxingxinghuo Silicone Co., Ltd. RTV108, molecular weight 1 million) in tetrahydrofuran (THF) and stir at room temperature to obtain a uniform and transparent solution (second spinning solution) with a mass concentration of 45%. 550,000) was dissolved in N,N-dimethylformamide with stirring in an oil bath at 50°C to obtain a uniform and transparent solution (the first spinning solution) with a mass concentration of 30%. The two prepared polymer solutions (the first spinning solution and the second spinning solution) were mixed according to the ratio of PVDF / PDMS mass ratio of 4:1, and the mixed solution was magnetically stirred at room temperature for 2 hours to obtain a uniform and transparent spinning solution. Silk dope (blended dope). 5 mL of the above mixed spinning solution was extracted with a 10 mL syringe for electrospinning, and the fiber filaments were received into a film-like structure to obtain a blended fiber membrane, and the thick...

Embodiment 3

[0054] Dissolve PDMS (Jiangxi Lanxingxinghuo Silicone Co., Ltd. RTV108, molecular weight 1 million) in tetrahydrofuran with stirring at room temperature to obtain a uniform and transparent solution with a mass concentration of 50%, and dissolve PVDF powder (molecular weight 550,000) in N,N-di The homogeneous and transparent solution with a mass concentration of 25% was obtained by stirring and dissolving in methylformamide in an oil bath at 50°C. The prepared two polymer solutions were mixed in a ratio of PVDF / PDMS mass ratio of 5:1, and the mixed solution was magnetically stirred at room temperature for 2 hours to obtain a uniform and transparent spinning solution. 5 mL of the above mixed spinning solution was extracted with a 10 mL syringe for electrospinning, and the fiber filaments were received into a film-like structure to obtain a blended fiber membrane, and the thickness of the blended fiber membrane was 0.1 mm. Electrospinning parameters were: spinning voltage 10 kV, ...

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Abstract

The invention relates to the technical field of functional materials, and specifically discloses a functional dressing and a preparation method thereof. The functional dressing of the present invention comprises: a fiber layer with piezoelectric properties and an organosilicon layer, the fiber layer is compounded with the organosilicon layer, and the organosilicon layer is used for contacting the application object; the fiber layer is a poly Vinylidene fluoride fiber membrane or polyvinylidene fluoride-polysiloxane blend fiber membrane. The functional dressing can simultaneously accelerate wound healing and reduce scarring, without the need for supporting charging equipment, easy to use, and the fiber layer and the silicone layer are tightly combined, with good air permeability and good biocompatibility. Tensile properties and strength, easy application and long service life. The preparation method of the functional dressing of the invention is simple and convenient, the production efficiency is high, the product quality is easy to control, and the uniformity is good, and the comprehensive performance of the functional dressing can be ensured.

Description

technical field [0001] The present invention relates to the technical field of functional materials. Specifically, it relates to a functional dressing and a preparation method thereof. Background technique [0002] NASA has developed a new type of medical bandage called electric bandage using polyvinylidene fluoride (PVDF) with piezoelectric properties. Experiments have shown that low-level electrical stimulation could theoretically help promote wound healing. In the weightless outer space, wound healing is extremely slow. Therefore, it is of great significance to develop new medical material bandages that accelerate wound healing. Polysiloxane (PDMS) dressing, also known as "Silicon Dressing", is a synthetic type of dressing based on polysiloxane. Polysiloxane-based materials have many excellent properties, such as transparency, elasticity, chemical inertness, and biocompatibility, and are widely used in the field of medical devices. At the same time, silicone dressings...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): D04H1/4318D04H1/4374D04H1/4382D04H1/728A61F13/00A61F13/02A61N1/18D01D5/00
CPCD04H1/4318D04H1/4374D04H1/4382D04H1/728D01D5/003D01D5/0069D01D5/0061D01D5/0092A61N1/18A61F13/02A61F13/0286A61F13/00038
Inventor 涂世俭陈立义陈胜宋振虎汪仲权
Owner ZHONGHAO CHENGUANG RES INST OF CHEMICALINDUSTRY CO LTD
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