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Device for artificially synthesizing platelets in vitro in fluid motion mode

An artificial synthesis and fluid motion technology, applied in the field of machinery, can solve the problems that the scale of platelet production cannot reach clinical use, hinder the clinical use of artificially produced platelets, etc., and achieve the effect of huge output.

Pending Publication Date: 2021-04-16
南京市江宁医院
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the production scale of platelets has not reached the scale of clinical use, which seriously hinders the clinical use of artificially produced platelets.

Method used

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  • Device for artificially synthesizing platelets in vitro in fluid motion mode
  • Device for artificially synthesizing platelets in vitro in fluid motion mode
  • Device for artificially synthesizing platelets in vitro in fluid motion mode

Examples

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Embodiment Construction

[0026] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the drawings in the embodiments of the present invention.

[0027] Such as figure 1 As shown, a device for artificially synthesizing platelets in vitro in a fluid motion mode, including an industrial computer 2 whose specific model is Siemens 6AG4010-4AA11-0XX5, a main control box 1, a reaction tank 11, a movable splint 4, a base 5, a rocker mechanism 44, Column 9 and vibration master bar 31 etc.; Described Siemens 6AG4010-4AA11-0XX5 industrial computer 2 is the main operating device of the whole device, wherein the main control box 1 is positioned at the upper end of the column 9, and the main control box 1 The lower end is provided with the main vibration rod 31, and the bottom end of the column 9 is provided with the base 5; the movable splint 4 is located in the middle of the column 9, and is connected with the long chute 30 in the...

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Abstract

The invention relates to the technical field of machinery, and discloses a device for artificially synthesizing platelets in vitro in a fluid motion mode, which is characterized by comprising an industrial personal computer, a main control box, a reaction tank, a movable clamping plate, a base, a rocker mechanism, a stand column, a vibration main rod and the like, wherein the main control box is located at the upper end of the stand column, the vibration main rod is located at the lower end of the main control box and in front of the stand column; and the movable clamping plate is located in the middle of the stand column and connected with a long sliding groove in the middle of the stand column through a sliding strip. The device can simulate a blood turbulence system in a body, induce generation of platelets, forcibly prevent quasi-platelet aggregation and apply kinetic energy forcing the quasi-platelet to split to obtain clean platelets; wherein the platelets can be directly applied to clinical application, and the platelets are not screened by an in-vivo immune system, so that the platelets can be rapidly separated from the platelets; the generated platelets have no obvious antigenicity, and no platelet antibody is generated.

Description

technical field [0001] The invention relates to the technical field of machinery, in particular to a device for artificially synthesizing platelets in vitro in a fluid motion mode. Background technique [0002] At present, the platelets used clinically all come from the platelet donation in voluntary blood donation. Because donating platelets takes a long time, the wound is large, and the process of returning to the donor body through extracorporeal circulation makes the source of platelets scarce. Nowadays, platelets are clinically used. has been in short supply. Secondly, many patients with blood diseases need long-term regular platelet transfusions, which can easily produce anti-platelet antibodies, resulting in ineffective platelet transfusions and posing a major threat to the safety of patients' lives and properties. Therefore, it is imperative to synthesize platelets in vitro. In recent years, some scientists have used the maturity of human induced pluripotent stem c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M3/00C12M1/00
Inventor 印澄
Owner 南京市江宁医院
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