Genotyping method, device, electronic device and storage medium

Abstract

Embodiments of the present invention provide a genotyping method, device, electronic device, and storage medium, wherein the above-mentioned genotyping method includes: acquiring a sequence to be typed, a reference sequence in a preset gene bank, and a first difference The result set, the preset gene library includes multiple candidate reference sequences, the first difference result set includes multiple first difference results corresponding to the multiple candidate reference sequences respectively, and the first difference results are used to characterize the corresponding candidate reference sequences and benchmarks Difference between reference sequences; obtain the second difference result between the sequence to be typed and the reference reference sequence; determine the target reference sequence from multiple candidate reference sequences, and the target reference sequence is the corresponding first difference result and the second difference result Candidate reference sequences that satisfy the first preset condition between the differences; determine the typing result of the sequence to be typed according to the target reference sequence. The embodiments of the present invention can effectively reduce the processing amount of data and improve the efficiency of comparison and genotyping.

Description

technical field [0001] The present invention relates to the technical field of gene detection, in particular to a genotyping method, device, electronic device and storage medium. Background technique [0002] It is well known that a large number of gene sequences, such as human leukocyte antigen (HLA) gene sequences, exist in gene banks such as the International Immunogenetics Information System (IMGT); The genotyping results of the gene sequences can be obtained by comparing the gene sequences. In the prior art, the sequenced gene sequences are usually compared with the gene sequences in the gene bank one by one. Due to the large number of gene sequences in the gene bank, the typing efficiency of the sequenced gene sequences is low. SUMMARY OF THE INVENTION [0003] Embodiments of the present invention provide a genotyping method, device, electronic device and storage medium, so as to solve the problem of comparing the sequence of the gene sequenced with the gene sequenc...

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Problems solved by technology

[0003] Embodiments of the present invention provide a genotyping method, device, electronic equipment, and storage medium to solve the problem of comparing the gene sequencing sequence with the gene sequence in the gene bank one by one in the prior art, due to the gene sequence in the gene bank The large number leads to the problem of low typing efficiency of gene sequencing sequences

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