Dispersion compensation method based on Fourier domain optical coherence tomography technology

Abstract

The invention discloses a dispersion compensation method based on a Fourier domain optical coherence tomography technology, which belongs to the technical field of optical coherence tomography. An interference signal is obtained according to a light intensity signal of output light of a Fourier domain optical coherence tomography system, then the interference signal is converted to obtain a complex interference signal, namely an analytic signal, a relation between a phase and a wave number is extracted, and third-order polynomial fitting is carried out; and finally, phase compensation is conducted on the analytic signal by utilizing the calculated second-order dispersion factor and third-order dispersion factor to realize the effect of eliminating the influence of high-order dispersion inthe Fourier domain optical coherence tomography imaging system and achieve the purpose of improving the axial resolution of the Fourier domain optical coherence tomography imaging system. The method is simple in operation mode, and dispersion compensation in continuous real-time imaging can be realized only by one-time measurement and calibration in an experiment.

Description

technical field [0001] The invention belongs to the technical field of optical coherence tomography, and relates to a dispersion compensation method based on Fourier domain optical coherence tomography. Background technique [0002] Optical coherence tomography (OCT) technology is a mainstream optical imaging technology, which has the advantages of high resolution, non-contact and real-time imaging, and is widely used in biomedicine and medical fields. The first generation of OCT technology is time domain OCT (time domain OCT, TD-OCT). The axial scanning of the sample is realized by mechanically moving the mirror of the reference arm. The imaging speed of this scanning method is limited by the scanning speed, and it will also The introduction of scanning noise limits the development of TD-OCT technology. The second-generation OCT technology is Fourier domain OCT (fourier domain OCT, FD-OCT), including spectral domain OCT (spectral domain OCT, SD-OCT) and swept frequency dom...

AI Technical Summary

Problems solved by technology

[0005] In view of the above-mentioned dispersion mismatch problem in Fourier domain OCT, as well as the disadvantages of the traditional hardware compensation method, such as the need to measure the refractive index of the sample, resulting in high cost, and the large amount of calculation in the traditional software compensation method, the present invention proposes a Based on the dispersion compensation method of Fourier domain optical coherence tomography technology, the relationship between phase and wavenumber is obtained by processing the interference signal, and the third-order polynomial fitting is performed on the phase and wavenumber to obtain high-order dispersion factors for phase compensation. , thereby eliminating the influence of high-order dispersion and improving the axial resolution of the Fourier domain OCT system

Images