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Method

A container and holder technology, applied in the field of pathogen detection, can solve the risk of hazardous events and other problems, and achieve the effect of rapid and low-cost on-site diagnosis

Active Publication Date: 2021-03-02
BG RESEARCH LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0015] These typical known reaction vessels are not suitable for use in the field with dangerous pathogens, especially since even though the user may be wearing a biohazardous suit, he may carry the reaction vessel for at least a short distance and therefore risk a hazardous event

Method used

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Embodiment Construction

[0025] In a first aspect, the invention provides a container comprising:

[0026] Reaction chamber part;

[0027] a lid holder portion having means for attaching the lid in such a way that there are at least two safety points between the lid and the reaction chamber portion when the lid is engaged with the container;

[0028] and cover.

[0029] In one embodiment, the container can be any type of container and can be made to hold any type of sample. For example, a container may be suitable for containing liquids, solids or gases. In a preferred embodiment, the container is adapted to contain a liquid. The container may be suitable for containing both liquids and solids, for example may be suitable for containing a lyophilized powder of, for example, a PCR component, to which liquid is subsequently added.

[0030] In one embodiment, the container is a reusable non-disposable container. Since in one embodiment the container will be used to detect harmful pathogens, in a pre...

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Abstract

The present invention relates to bio-secure means for the detection of pathogens and provides a bio-secure reaction vessel and methods of preparing a sample for PCR-based pathogen detection. The reaction vessel comprises a reaction chamber portion (1); a cap holder portion (2); and a cap (3). Two points of security, such as two O-ring seals (9, 10), are provided between the cap (3) and the reaction chamber portion (1). A first seal (9) may be located at a top of the cap holder portion (2) and a second seal (10) may be located at a base of the cap (10).

Description

technical field [0001] The invention relates to the field of pathogen detection. Background technique [0002] Typically, molecular methods used to screen for the presence of high-protection pathogens such as Ebola virus (Ebola) require an additional level of biosecurity to protect the operators performing the tests. The first step in screening for these viral hemorrhagic fevers is to draw venous blood from the patient. Individuals collecting samples typically wear full personal protective equipment, including multiple pairs of gloves, gowns, and masks. After blood samples are collected, the exterior of the collection container is sanitized by soaking in bleach and then a viricide (eg, guanidine isothiocyanate) to render the virus non-infectious prior to nucleic acid extraction. These known methods involve multi-step procedures and therefore require trained users and access to laboratories. [0003] Typical volumes of IV aspirate fluid used for this type of testing are 3 ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00C12Q1/686B01L7/00
CPCB01L3/5021B01L3/508B01L2200/141C12Q1/686B01L2200/0689B01L2300/021B01L2300/042B01L2300/0832B01L2300/12B01L2400/0409B01L7/52B01L2200/10C12Q2561/113C12Q2563/107C12Q1/6806
Inventor N·纳扎雷斯D·艾德格A·泰勒M·塞德乐
Owner BG RESEARCH LTD
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