Preparation method and application of folium cortex eucommiae extract for preventing and treating hypertension kidney injury

A technology of eucommia leaves and extracts, which is applied in the field of preparation of eucommia leaves extracts for preventing and treating hypertensive kidney damage, can solve the problem that the improvement of extrarenal symptoms is not obvious, and achieve the effect of simple preparation method

Pending Publication Date: 2021-01-22
天津益倍元天然产物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, Western medicine mainly uses angiotensin-converting enzyme inhibitors and calcium ion antagonists to treat hypertensive renal damage. Their effects are mainly reflected in the effective reduction of blood pressure and improvement of renal function, but the improvement of symptoms outside the kidney is not obvious.

Method used

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  • Preparation method and application of folium cortex eucommiae extract for preventing and treating hypertension kidney injury
  • Preparation method and application of folium cortex eucommiae extract for preventing and treating hypertension kidney injury
  • Preparation method and application of folium cortex eucommiae extract for preventing and treating hypertension kidney injury

Examples

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Embodiment 1

[0016] A preparation method of eucommia leaf extract for preventing and treating hypertensive kidney injury, the steps are: take a certain amount of eucommia leaves, extract the eucommia leaves with 15 times the mass of water, reflux at 100°C for 2 hours, filter and take the filtrate for use, and then pour the eucommia leaves Add 15 times the mass of water to the leaves, boil and reflux for the second time, collect the filtrate by filtration, mix the two filtrates, concentrate by rotary evaporation at 65°C under vacuum, and then spray dry to obtain the Eucommia leaf extract.

[0017] The eucommia leaf extract is filtered with at least 200 mesh filter screen or filter cloth.

[0018] The application of the eucommia leaf extract in the preparation of medicines or health food for preventing and treating hypertensive kidney damage.

[0019] The eucommia leaf extract and the approved excipients in medicaments or health foods are made into various dosage forms mainly composed of euc...

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Abstract

The invention discloses a preparation method and application of folium cortex eucommiae extract for preventing and treating hypertension kidney injury. The preparation method comprises the following steps of taking a certain amount of folium cortex eucommiae, extracting the folium cortex eucommiae with water of which the mass is 15 times that of the folium cortex eucommiae, performing refluxing for 2 hours at 100 DEG C, performing filtering to obtain filtrate for later use, adding water of which the mass is 15 times that of the folium cortex eucommiae, performing secondary boiling reflux, performing filtering, collecting the filtrate, mixing the two filtrates, performing concentrating and spray-drying, thereby obtaining folium cortex eucommiae extract. The folium cortex eucommiae extract disclosed by the invention is simple in preparation method, natural and energy-saving, can prevent and treat renal injury of spontaneously hypertensive rats, and can be used for preparing medicines orhealth-care foods for preventing and treating the hypertensive renal injury.

Description

technical field [0001] The invention relates to the field of health food, in particular to a preparation method and application of Eucommia leaf extract for preventing and treating hypertensive kidney damage. Background technique [0002] The prevalence of hypertension among adults in my country is about 18.8%, and it is increasing year by year. Kidney damage is one of the major complications of hypertension. At present, most antihypertensive drugs mainly evaluate the antihypertensive effect, and less attention is paid to the renal damage caused by hypertension. The kidney is one of the target organs damaged by hypertension. Generally speaking, most hypertensive patients who have lasted for more than 5 years have varying degrees of kidney damage. At present, Western medicine mainly uses angiotensin-converting enzyme inhibitors and calcium ion antagonists to treat hypertensive renal damage. Their effects are mainly reflected in the effective reduction of blood pressure and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/46A23L33/105A61P9/12A61P13/12A61K127/00
CPCA61K36/46A23L33/105A61P9/12A61P13/12A61K2236/331A61K2236/39A61K2236/53A61K2236/51A23V2002/00A23V2200/326A23V2250/21
Inventor 张东星郑艳超晏仁义李赫宇王磊胡丹
Owner 天津益倍元天然产物技术有限公司
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