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Mixing device and method for clotrimazole cream production

A mixing device and clotrimazole technology, which is applied in the field of mixing devices for clotrimazole cream production, can solve problems affecting production quality, waste of cream medicine, and sticking of cream liquid, so as to prevent sticking and ensure production quality , Prevent the effect of stirring dead angle

Active Publication Date: 2021-01-15
河南大新药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The cream concentration after stirring is high, and a large amount of cream liquid will adhere to the inner cavity wall of the equipment when the cream is discharged, resulting in a large amount of waste of cream medicine, and the medicine remaining inside the equipment will directly affect the subsequent production quality

Method used

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  • Mixing device and method for clotrimazole cream production
  • Mixing device and method for clotrimazole cream production
  • Mixing device and method for clotrimazole cream production

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] See Figure 1-3 , a mixing device for the production of clotrimazole emulsifiable paste, comprising a kettle body 1, the bottom of the kettle body 1 is evenly provided with several legs 2, and the bottom of the kettle body 1 is connected to a discharge pipe 19 through, and the The bottom end of the discharge pipe 19 is covered with a second sealing cover 20, and the cream that has been stirred in the inner cavity of the kettle body 1 is discharged through the discharge pipe 19, and the discharge work can be completed;

[0036] The top of the kettle body 1 is fixedly connected to the mixing motor 3, the inner cavity of the kettle body 1 is provided with a stirring rod 4, the axis of the kettle body 1 coincides with the axis of the stirring rod 4, and the top of the stirring rod 4 runs through the bottom of the kettle body 1. The top wall is rotatably connected to the mixing motor 3, the stirring rod 4 is rotatably connected to the kettle body 1 through the bearing 5, the...

Embodiment 2

[0042] See Figure 4 , The difference from Embodiment 1 is that the stirring belt 13 includes a first base belt 131, a second base belt 133, a third base belt 136, a first waterproof membrane 132, a second waterproof membrane 134, a third waterproof membrane 135 and a first waterproof membrane 135. Four waterproof membranes 137, the first base belt 131 is made of nylon webbing, the top of the first base belt 131 is provided with a first waterproof membrane 132, and the bottom end of the first base belt 131 is provided with a third waterproof membrane 135, so Both the first waterproof membrane 132 and the third waterproof membrane 135 are made of polyester film, the top of the first waterproof membrane 132 is provided with a second base belt 133, and the second base belt 133 is made of nylon webbing, The top of the second baseband 133 is provided with a second waterproof membrane 134, the second waterproof membrane 134 is made of PVA coated high barrier film, the bottom end of ...

Embodiment 3

[0044] See Figure 5 The difference from Embodiment 1 is that the stirring blade 14 includes a blade plate 141, the blade plate 141 is arranged in an arc-shaped structure, and the left and right sides of the concave surface of the blade plate 141 are symmetrically provided with fixed plates 142, and the fixed plate The top end of 142 is provided with the mounting groove 143 that matches with stirring belt 13, and described connecting rod 15 is fixedly connected on the concave surface of blade plate 141, and described blade plate 141 is provided with stirring hole 144, and described stirring hole 144 runs through connecting blade. The front and rear end surfaces of the plate 141, the stirring hole 144 is an arc-shaped hole, the blade plate 141 is driven to rotate by the stirring rod 4 and the connecting rod 15, and then the blade plate 141 is used to stir the raw material at the bottom of the inner cavity of the kettle body 1, which can effectively prevent the dead angle of stir...

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Abstract

The invention discloses a mixing device and method for clotrimazole cream production. The mixing device comprises a kettle body, a mixing motor is fixedly connected to the top end of the kettle body,a stirring rod is arranged in an inner cavity of the kettle body, a power cavity and a sliding groove are formed in the stirring rod, a stirring plate matched with the kettle body is arranged on the outer side of the stirring rod in a sleeving mode, and a sleeve hole is formed in the stirring plate; and a sliding rod matched with the sliding groove is arranged in the sleeve hole, the top wall of an inner cavity of the power cavity is fixedly connected with an electric telescopic device, and the bottom end of a telescopic rod on the electric telescopic device penetrates through the bottom wallof the power cavity and is fixedly connected to the sliding rod. The telescopic rod extends out of the electric telescopic device, then the telescopic rod is used for pushing the sliding rod to descend along the sliding groove, then a stirring plate is pushed to descend along the inner cavity wall of the kettle body, cream in the inner cavity of the kettle body can be extruded by the stirring plate to be discharged from a discharging pipe, and the cream can be effectively prevented from adhering to the inner cavity wall of the kettle body; and thus the cream in the kettle body can be completely discharged, and the yield of the cream can be effectively guaranteed.

Description

technical field [0001] The invention relates to the technical field of clotrimazole production equipment, in particular to a mixing device and method for clotrimazole cream production. Background technique [0002] Clotrimazole cream is an over-the-counter drug for gynecology. For candidal vulvovaginal disease, especially suitable for vaginal dryness or menopausal women who are inconvenient to use clotrimazole vaginal tablets. The drug is a broad-spectrum antifungal drug, and its mechanism of action is to inhibit the synthesis of fungal cell membrane and affect its metabolic process. It has antibacterial effect on superficial and deep fungi. [0003] In the production process of clotrimazole cream, mixing equipment is required to mix and stir the raw materials carefully to promote the mixing reaction of each raw material. The cream concentration after stirring is high, and a large amount of cream liquid will adhere to the inner wall of the equipment when the cream is disc...

Claims

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Application Information

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IPC IPC(8): B01F15/02B01F7/18
CPCB01F27/192B01F27/90B01F35/754B01F2101/22
Inventor 阎桂芬白春燕
Owner 河南大新药业有限公司
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