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Facultative-aerobic microorganism coexistence fermentation tank

An aerobic microorganism and fermenter technology, which is applied in the direction of bioreactor/fermenter combination, specific-purpose bioreactor/fermenter, enzymology/microbiology device, etc., can solve the problems of increasing the degree of oxygen dissolution, complex structure, Problems such as low oxygen demand

Pending Publication Date: 2021-01-05
DEZHOU VOCATIONAL & TECHN COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, conventional fermentation equipment is divided into aerobic and anaerobic types. Since different types of fermentation equipment have different structures and functions, when performing fermentation work, it is usually necessary to configure different types of fermentation equipment to complete different types of fermentation. process, but many fermentation equipment are complex in structure and expensive, and multiple different types of fermentation equipment will also occupy a large area of ​​space
In the biopharmaceutical and other fermentation industries, it is necessary to ferment the cultured strains. The fermentation process is carried out in a fermenter. The fermentation process requires oxygen, so it is necessary to feed clean air or an appropriate concentration of oxygen into the fermenter. Supplement the lack of oxygen in the fermentation tank due to fermentation. In order to make the fermentation uniform, many fermentation equipment are equipped with complex stirring devices to increase the degree of oxygen dissolved in water.
[0003] Aerobic microorganisms need sufficient oxygen during the fermentation process, while facultative microorganisms have low oxygen requirements and different types of facultative microorganisms require different oxygen concentrations for fermentation. Anaerobic respiration fermentation is carried out in an oxygen environment, and the fermentation tank specially customized for the cultivation of the above two microorganisms greatly increases the production cost

Method used

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  • Facultative-aerobic microorganism coexistence fermentation tank
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  • Facultative-aerobic microorganism coexistence fermentation tank

Examples

Experimental program
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Effect test

Embodiment 1

[0027] combined with Figure 1-7 , a facultative-aerobic microbial coexistence fermenter, comprising a tank body 1, the middle part of the tank body 1 is provided with a partition 11, the middle and lower part of the partition 11 is provided with a temperature sensor 10, and the upper part of the partition 11 slides Connect the sealing plate 12, the top of the sealing plate 12 is fixedly connected to the lead screw 13 in the middle, one side of the tank body is fixedly connected to the air inlet pipe 14, and the bottom of the air inlet pipe 14 in the tank body 1 is fixedly connected to the herringbone type air outlet device 15. The bottom of the tank body 1 is fixedly connected with a discharge pipe 1 16 and a discharge pipe 2 17 respectively, and the top of the tank body 1 is connected to the tank cover 2 with bolts, and the tank cover 2 is respectively provided with a feed hopper 1 21 and a feed hopper 2 22. A through-type linear motor 23 is fixedly installed in the upper mi...

Embodiment 2

[0040] For Example 1, different facultative microorganisms have different oxygen requirements during the fermentation process, and the oxygen concentration on the chamber side of the facultative microorganism solution can be changed in the following manner:

[0041] First, make the sealing plate at the lowest position and the tanks on both sides of the partition are in a connected state: ① Close the sealing cover 1 and open the sealing cover 2. At this time, the air needs to be discharged through the side cavity of the facultative microorganisms, the air circulation is good, and the oxygen concentration is low. High; ②Sealing cover 1 and sealing cover 2 are both open, at this time, there is air circulation in the cavities on both sides of the partition in the tank, and the air flow rate on the side of the facultative microorganisms is low, and the oxygen concentration is low; ③Open the sealing cover 1, close the sealing Cover 2. At this time, the air flow in the side chamber of...

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Abstract

The invention provides a facultative-aerobic microorganism coexistence fermentation tank, and mainly relates to the field of microorganism culture containers. The facultative-aerobic microorganism coexistence fermentation tank comprises a tank body, wherein a partition plate is arranged in the middle in the tank body, a sealing plate is arranged on the upper part of the partition plate in a slidemanner, a lead screw is fixedly connected with the middle of the top of the sealing plate, an air inlet pipe is arranged on one side of the tank body, fishbone-shaped air outlet apparatus is fixedly connected with the bottom of the air inlet pipe in the tank body, discharge pipes are arranged at the bottom of the tank body, a tank cover is arranged at the top of the tank body, feeding hoppers arearranged on the tank cover, a through type linear motor is arranged on the tank cover, and a pressure gauge and a pressure release valve are arranged on the tank cover. The facultative-anaerobic microorganism coexistence fermentation tank has the beneficial effects that through the tank body structure, an air flow in a facultative microorganism cavity is greatly adjusted on the basis of ensuring sufficient oxygen supply of an aerobic microorganism side cavity, so that different oxygen concentrations required by facultative microorganism fermentation are met, and thereby the simultaneous culture of facultative microorganisms and aerobic microorganisms is realized.

Description

technical field [0001] The invention mainly relates to the field of microbial culture containers, in particular to a facultative-aerobic microbial coexistence fermenter. Background technique [0002] Fermentation refers to the process in which people use the life activities of microorganisms under aerobic or anaerobic conditions to prepare the microbial cells themselves, or direct metabolites or secondary metabolites. At present, conventional fermentation equipment is divided into aerobic and anaerobic types. Since different types of fermentation equipment have different structures and functions, when performing fermentation work, it is usually necessary to configure different types of fermentation equipment to complete different types of fermentation. process, but many fermentation equipment are complex in structure and expensive, and multiple different types of fermentation equipment will also occupy a large area of ​​space. In the biopharmaceutical and other fermentation...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/00C12M1/04
CPCC12M23/34C12M23/38C12M29/06
Inventor 吕伟
Owner DEZHOU VOCATIONAL & TECHN COLLEGE
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