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Application of magnesium hydride in preparation of composition for preventing and treating chronic periodontitis, and magnesium hydride toothpaste

A technology of chronic periodontitis and magnesium hydride, which is applied in the field of toothpaste, can solve the problems of single function, inaccurate efficacy, and unknown ingredients of traditional Chinese medicine, and achieve the effects of preventing occurrence and development, improving gingival bleeding, and alleviating periodontal disease

Inactive Publication Date: 2020-12-11
SHANGHAI JIAO TONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But its function is single and its service life is short
Another kind of scheme is to use Chinese medicine composition (as documented in the patent document CN102860971A a kind of by adding and adopting natural propolis and Chinese medicine with analgesic, anesthesia, antiallergic effect as main efficacy preparation, compound traditional western medicine, supplemented by biotechnology to make Compound toothpaste with antibacterial, anti-inflammatory and anti-acid desensitization), its disadvantage is that various traditional Chinese medicine additives may cause obvious side effects, and the ingredients of traditional Chinese medicine are unknown, and the efficacy is not exact, which makes this kind of products unable to enter the international market

Method used

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  • Application of magnesium hydride in preparation of composition for preventing and treating chronic periodontitis, and magnesium hydride toothpaste
  • Application of magnesium hydride in preparation of composition for preventing and treating chronic periodontitis, and magnesium hydride toothpaste
  • Application of magnesium hydride in preparation of composition for preventing and treating chronic periodontitis, and magnesium hydride toothpaste

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Embodiment 1: configure a kind of toothpaste, be made up of following component by weight percentage: 51% glycerin, 42% calcium carbonate, 2% silicon dioxide, 3% sodium lauryl sulfate, 1% magnesium hydride (granule grain The diameter is 10-30um), 1% mint powder.

[0037] Toothpaste is prepared as follows:

[0038] Magnesium hydride particles are composed of MgH2 compound particles with a particle size of 0.1-100um. The toothpaste body can be prepared by adopting the traditional toothpaste preparation process. Specifically, the preparation method of the magnesium hydride type toothpaste of this embodiment is as follows: after weighing the above-mentioned raw material components, disperse and mix in a pre-dispersion kettle, and open the paste kettle to suck the above-mentioned liquid material by a vacuum pump. Then open scraper, agitator and colloid mill, and turn off colloid mill, agitator and scraper successively after 50 minutes, break vacuum, obtain magnesium hydrid...

Embodiment 2

[0039] Embodiment 2: configure a kind of toothpaste, be made up of following component by weight percentage: 33.4% paraffin oil, 14.3% glycerine, 43% calcium carbonate, 2% silicon dioxide, 3% sodium lauryl sulfate, 1% Sodium carboxymethyl cellulose, 0.3% xanthan gum, 2% magnesium hydride (particle size is 10-30um), 1% peppermint powder.

[0040] According to the preparation method of example 1, obtain the magnesium hydride type toothpaste of example 2.

Embodiment 3

[0041] Embodiment 3: configure a kind of toothpaste, be made up of following component by weight percentage: 29% 1,2-propanediol, 15% glycerol, 44% calcium carbonate, 5% silicon dioxide, 3% polyvinylpyrrolidone, 3% Magnesium hydride (particle size 10-30um), 1% peppermint powder.

[0042] According to the preparation method of example 1, obtain the magnesium hydride type toothpaste of example 3.

[0043] The toothpaste of the present invention is added with magnesium hydride, which can resist oxidation, remove tooth stains and whiten, effectively inhibit inflammation, have good stability, and can effectively prevent a series of clinical symptoms caused by delayed periodontitis.

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Abstract

The invention provides application of magnesium hydride in preparation of a composition for preventing and treating chronic periodontitis, and magnesium hydride toothpaste. The weight percentage of magnesium hydride in the composition or the magnesium hydride toothpaste is 1-3%. The toothpaste has the effects of sterilizing, resisting inflammation, resisting oxidation, removing tooth stains, improving breath or halitosis, relieving redness, swelling and bleeding of gingiva and gingival recession, and improving periodontitis symptoms. The invention also discloses application of magnesium hydride in preparation of a composition for preventing and treating chronic periodontitis. According to the invention, a proper amount of magnesium hydride fine particles are added into the toothpaste body;and the magnesium hydride particles can be hydrolyzed into hydrogen and magnesium ions with an anti-inflammatory effect, and also can inhibit alveolar bone absorption. The composition containing magnesium hydride is safe to use, and can effectively prevent the occurrence and development of periodontal diseases after long-term use.

Description

technical field [0001] The invention relates to the technical field of toothpaste, in particular to the application of magnesium hydride in the preparation of a composition for preventing and treating chronic periodontitis and the magnesium hydride toothpaste. Background technique [0002] The effect of brushing teeth is to clean teeth and maintain oral hygiene. Toothpaste is a necessity in human daily life. With the improvement of people's living standards, changes in dietary content, neglect of oral hygiene, or oral flora imbalance have led to a significant increase in the prevalence of periodontal disease, and it presents characteristics regardless of age, gender, or sex. [0003] Periodontal disease is mainly a series of clinical symptoms such as gum bleeding, swelling, and ulcers caused by bacterial infection. In addition, periodontal disease can also lead to alveolar bone resorption, which in turn causes tooth loosening and loss. In particular, periodontal disease wi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/06A61K8/19A61K8/9789A61P1/02A61P29/00A61P31/02A61P31/04A61P39/06A61Q11/00
CPCA61K33/06A61P1/02A61P29/00A61P31/04A61P31/02A61P39/06A61K8/19A61K8/9789A61Q11/00A61K2800/412A61K2800/413A61K8/0241Y02A50/30A61K8/25A61K8/345A61K8/463A61K8/73A61K8/731A61K8/8176A61K2800/28A61K2800/75
Inventor 袁广银丁文江李月玲沈丽
Owner SHANGHAI JIAO TONG UNIV
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