Application of RPS3A molecule in prediction of immune cell infiltration and immune checkpoint molecular expression level in tumors and predicting model
An RPS3A, immune checkpoint technology, applied in the field of biomedicine, can solve the problem of little research on accurate evaluation system, achieve good prediction efficiency and accuracy, multiple clinical net benefits, and improve the effect of prediction effect
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[0035] 1. Research object:
[0036] The research objects of this embodiment are 154 postoperative tumor tissues of patients with hepatocellular carcinoma, and the inclusion and exclusion criteria are:
[0037] (1) No history of other malignant tumors;
[0038] (2) Never received cancer treatment before operation, and no extrahepatic metastasis was found before operation;
[0039] (3) There is no sign of infection or other inflammation except viral hepatitis;
[0040] (4) Radical resection;
[0041] (5) The postoperative pathological diagnosis was hepatocellular carcinoma.
[0042] 2. Research methods:
[0043] (1) Surgically resected tumor tissue samples from patients with hepatocellular carcinoma were collected, fixed in paraformaldehyde, and embedded in paraffin to construct tissue microarray chips.
[0044] (2) Collect clinicopathological information and postoperative follow-up data of patients with hepatocellular carcinoma
[0045] Routine clinicopathological informa...
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