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Pharmaceutical composition for improving sleep and preparation method and application of pharmaceutical composition

A technology for improving sleep and composition, applied in the field of pharmaceutical composition for improving sleep and preparation thereof, can solve the problems of inconvenience to patients, poor compliance, and difficult to store, and achieve the effect of improving sleep

Inactive Publication Date: 2020-11-24
CHENGDU RUNXINTANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, traditional Chinese medicine fumigation, acupuncture, massage, acupoint sticking, etc. require professional operation, which is not convenient for patients to carry out at home. It is cumbersome and may cause problems such as poor compliance.
Oral administration of traditional Chinese medicine decoction is convenient for patients to take, but there are problems such as the influence of personnel operation during decoction, uneven extraction rate of medicinal components, inconvenient taking of decoction, and difficulty in preservation.
CN101773559A, CN102133320A, and CN102370781A all disclose that Schisandra chinensis, jujube seed, twig vine, Albizia julibrissin and other drugs are jointly prepared into a drug for treating insomnia. Although it has a certain effect, it is not ideal and needs to be further improved.
Although CN1408397A discloses that melatonin is added into a Chinese medicine composition to treat insomnia together, there are problems such as large prescriptions of the medicine and incomplete research on improving sleep.

Method used

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  • Pharmaceutical composition for improving sleep and preparation method and application of pharmaceutical composition
  • Pharmaceutical composition for improving sleep and preparation method and application of pharmaceutical composition
  • Pharmaceutical composition for improving sleep and preparation method and application of pharmaceutical composition

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Effect test

Embodiment 1

[0026] Embodiment 1, the preparation of pharmaceutical composition of the present invention

[0027] Raw material formula: melatonin 0.03g, schisandra 5g, jujube seed 20g, kudzu root 20g, twig vine 20g, albizia julibrissin 15g, amomum 5g.

[0028] Preparation method: Schisandra chinensis, wild jujube seed, kudzu root, night cross vine, albizia julibrissin, and amomum were weighed according to the above formula, decocted and extracted twice, each time with 10 times the amount of water (that is, adding 10 mL of water per 1 g of total raw material drug) water) extraction for 2 hours, after the extraction is completed, the extracts are combined, concentrated, powdered, and melatonin and auxiliary materials are added to prepare capsules.

Embodiment 2

[0029] Embodiment 2, the preparation of pharmaceutical composition of the present invention

[0030] Raw material formula: melatonin 0.01g, schisandra 1g, jujube seed 10g, kudzu root 10g, vine 10g, Albizia julibrissin 10g, amomum 1g.

[0031] Preparation method: with embodiment 1.

Embodiment 3

[0032] Embodiment 3, the preparation of pharmaceutical composition of the present invention

[0033] Raw material formula: melatonin 0.1g, schisandra 10g, jujube seed 30g, kudzu root 30g, twig vine 30g, albizia julibrissin 20g, amomum 10g.

[0034] Preparation method: with embodiment 1.

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Abstract

The invention provides a pharmaceutical composition for improving sleep and a preparation method and application of the pharmaceutical composition, and belongs to the field of traditional Chinese medicines. The pharmaceutical composition is a preparation prepared from the following raw material medicines in parts by weight: 0.01-0.1 part of melatonin, 1-10 parts of fructus schisandrae chinensis, 10-30 parts of semen ziziphi spinosae, 10-30 parts of radix puerariae, 10-30 parts of caulis polygoni multiflori, 10-20 parts of flos albiziae and 1-10 parts of fructus amomi. The pharmaceutical composition is precise and appropriate in compatibility of all medicinal materials, can effectively improve sleep and has a good effect on treating insomnia.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition for improving sleep, a preparation method and application thereof. Background technique [0002] Insomnia often appears in the main complaints of patients with various clinical diseases. According to survey statistics, about 65.4% of Chinese people have sleep problems to a certain extent. With the development of society and the acceleration of the pace of life, great changes have taken place in people's lifestyles. External pressure, mental work, and bad living habits have gradually increased the prevalence of insomnia, and the insomnia population is getting younger. [0003] Clinically, insomnia is prone to recurring and chronic, lingering and difficult to heal. Prolonged insomnia can cause irritability, depression, and malaise in patients, leading to hypertension, hyperlipidemia, obesity, cardiovascular and other diseases; it...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61P25/20A61K31/4045
CPCA61K31/4045A61K36/48A61K36/488A61K36/57A61K36/704A61K36/725A61K36/79A61K36/9064A61P25/20A61K2300/00
Inventor 徐亮何仲清朱志刘洋俸世洪黄浩
Owner CHENGDU RUNXINTANG PHARMA
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