Wormwood extract, and preparation method and applications thereof
A technology for extract and wormwood, applied in the field of wormwood extract and its preparation, can solve the problems of chemical component stimulation, easy to produce tolerance, difficult to determine effective components of traditional Chinese medicine compound compositions, etc., and achieve low irritation. Effect
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Embodiment 1
[0021] A kind of wormwood total extract, the preparation method of described wormwood extract comprises the following steps:
[0022] S1 Supercritical Extraction of Wormwood Volatile Oil: Ultrafinely pulverize the wormwood, put it into a supercritical extraction device, and extract it at a pressure of 18MPa, a temperature of 40°C, and CO 2 At a flow rate of 20kg / h, extract for 120min to obtain wormwood volatile oil extract and medicinal residues. The wormwood volatile oil extract is concentrated under reduced pressure at 40°C to an extract with a density of 1.4-1.8g / mL to obtain wormwood volatile oil; S2 extraction of dregs: add water to the dregs described in S1 according to the dregs: water mass ratio of 1:8, add water and reflux at 70°C to extract twice, each time for 2 hours, collect the extract, and concentrate under reduced pressure at 40°C to the density The extract is 1.5-1.8g / mL, and the dregs extract is obtained; the total extract of S3 is obtained by mixing the worm...
Embodiment 2
[0024] A kind of wormwood total extract, the preparation method of described wormwood extract comprises the following steps:
[0025] S1 Supercritical Extraction of Wormwood Volatile Oil: Ultrafinely pulverize the wormwood, put it into a supercritical extraction device, and extract it at a pressure of 24MPa, a temperature of 50°C, and CO 2 At a flow rate of 30kg / h, extract for 240min to obtain wormwood volatile oil extract and medicinal residues. The wormwood volatile oil extract is concentrated under reduced pressure at 60°C to an extract with a density of 1.4-1.8g / mL to obtain wormwood volatile oil; S2 extraction of dregs: add water to the dregs of S1 according to the dregs: water mass ratio of 1:20, add water and reflux at 90°C to extract twice, each time for 4 hours, collect the extract, and concentrate under reduced pressure at 60°C to the density The extract is 1.5-1.8g / mL, and the dregs extract is obtained; the total extract of S3 is obtained by mixing the wormwood vola...
Embodiment 3
[0027] A kind of wormwood total extract, the preparation method of described wormwood extract comprises the following steps:
[0028] S1 supercritical extraction of wormwood volatile oil: After the wormwood is ultrafinely pulverized, it is loaded into a supercritical extraction device, and the volatile oil is extracted at a pressure of 22MPa, a temperature of 45°C, and CO 2 At a flow rate of 28kg / h, extract for 180min to obtain wormwood volatile oil extract and medicinal residues. The wormwood volatile oil extract was concentrated under reduced pressure at 50°C to an extract with a density of 1.4-1.8g / mL to obtain wormwood volatile oil; S2 extraction of dregs: add water to the dregs described in S1 according to the dregs: water mass ratio of 1:10, add water and reflux at 80°C to extract twice, each time for 3 hours, collect the extract, and concentrate under reduced pressure at 50°C to the density 1.5-1.8g / mL extract, the dregs extract is obtained;
[0029] S3 total extract: ...
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