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Method and device for producing medical isotope 225Ac

An isotope and medical technology, applied in the field of methods and devices for the production of medical isotope 225Ac, can solve the problems of high cost and complicated process, and achieve the effect of low cost, low investment and high output

Active Publication Date: 2020-09-29
西安迈斯拓扑科技有限公司
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  • Abstract
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Problems solved by technology

[0005] In order to solve the current production 225 The method of Ac has problems such as high cost and complicated process. The invention discloses a method for producing medical isotopes 225 Ac method and apparatus for converting high-power high-energy electron beams to bremsstrahlung bombardment 226 Ra, via photonuclear reaction produce 225 Ac, the method not only does not require expensive 229 Th, and high output, low cost, simple and convenient, no radioactive waste disposal problems

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  • Method and device for producing medical isotope 225Ac
  • Method and device for producing medical isotope 225Ac
  • Method and device for producing medical isotope 225Ac

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Embodiment Construction

[0047] The present invention will be further described below in conjunction with the accompanying drawings and specific embodiments.

[0048] The invention utilizes high-energy electron beams to irradiate the bremsstrahlung conversion target to generate sufficient X-ray photon beams, and utilizes X-ray photon beams to irradiate 226 Ra sample target; after standing for 18 days, the radiation produced 225 Ra via β - decay into a certain amount 225 Ac, again 226 The Ra sample target is chemically dissolved and separated 225 Ac.

[0049] The photonuclear reaction cross-section is generally small, but a wide (3-7MeV) giant dipole resonance peak (GDR) appears in the energy range of 10-25MeV. Due to the phenomenon of the giant dipole resonance peak, the 226 The photonuclear reaction of Ra will have a relatively high photonuclear cross section, such as image 3 , 226 Ra(γ,n) 225 The photonuclear cross section of Ra is ~290mb. The threshold energy is 6.2MeV, and the peak cross...

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Abstract

The invention belongs to the field of medical radioactive therapy nuclide, particularly relates to a method and a device for producing medical isotope 225Ac, and solves the problems that an existing method for producing 225Ac is low in yield, high in cost and complicated in process and the like. High-power high-energy electron beams are converted into braking radiation to bombard a 226Ra sample target, 225Ac is generated through a photonuclear reaction, and finally, the 226Ra sample target is chemically dissolved to separate out 225Ac so that the method does not need expensive 229Th and is lowin cost, simple and convenient and does not have the problem of radioactive waste treatment.

Description

technical field [0001] The invention belongs to the field of medical radiotherapy nuclides, and in particular relates to a production of medical isotopes 225 Ac Methods and Apparatus. Background technique [0002] With the continuous update and development of modern medicine for tumor diagnosis and treatment, tumor treatment is developing towards precise targeted therapy. In addition to targeted chemotherapeutic drugs, targeted radionuclide therapy drugs have received more and more attention, and the prospects are very broad. A radioactive isotope that decays by the release of alpha particles, typically as 225 Ac and 213 Bi( 213 Bi is 225 The decay daughter of Ac) is rapidly becoming the trend and key field of tumor diagnosis and treatment, especially the research of tumor targeted therapy. Preclinical animal experimental research and preliminary clinical practice have achieved very successful results. This is mainly because: 1) 225 Ac has excellent nuclear physical p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G21G1/00
CPCG21G1/001G21G2001/0089
Inventor 张宇皓刘伯学王思弘王柏松
Owner 西安迈斯拓扑科技有限公司
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