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Pharmaceutical composition for treating pneumonia as well as preparation method and application thereof

A drug compound and pneumonia technology, applied in the direction of drug combination, medical formula, medical preparations with non-active ingredients, etc., can solve the problem of no treatment for new coronary pneumonia, achieve the removal of impurities in the lungs, smooth breathing, and recovery of the lungs. The effect of the function

Inactive Publication Date: 2020-09-25
辽宁钰航生物医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] There is currently no definitive treatment for COVID-19

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1 A kind of drug complex for the treatment of pneumonia

[0025] 1. A drug complex for the treatment of pneumonia

[0026] 5 parts of Bellflower, 5 parts of Aster, 5 parts of Baibu, 5 parts of Baiqian, and 5 parts of Licorice.

[0027] 2. Precipitation state of raw materials of traditional Chinese medicine

[0028] Boil Platycodon grandiflorum, Ziyuan, Baibu, Baiqian, and licorice until thick, cool down, and observe the state of drug precipitation.

[0029] Table 1 The precipitation state of each raw drug hydrogel

[0030] drug Is it a gel viscosity drug status Store TB aggregation at 4°C pH bellflower yes lower Brown precipitation No obvious aggregation within a week 6.9 Asters yes Moderate Brown precipitation Significant aggregation within a week 7.2 Hyakube yes Moderate Brown precipitation Gathering in a week 7.2 white front yes Moderate Brown precipitation No drug aggregation 7.2...

Embodiment 2

[0037] Embodiment 2 A kind of drug complex for the treatment of pneumonia

[0038] 1. A drug complex for the treatment of pneumonia

[0039] 5 parts of platycodon, 5 parts of aster, 5 parts of hundred parts, 5 parts of Baiqian, 5 parts of licorice, and 2 parts of fusion agent propylene glycol.

[0040] 2. Precipitation state of raw materials of traditional Chinese medicine

[0041] Boil 1 part of Platycodon grandiflorum, 1 part of aster, 1 part of Baibu, 1 part of Baiqian, and 1 part of licorice until thick, cool, add 2 parts of 50g / L propylene glycol, and add a blank control (distilled water) to facilitate observation; Stir evenly and observe the dissolution state of the drug. The precipitation state is shown in Table 2.

[0042] The precipitation state of table 2 raw drug

[0043] drug drug status Viscosity (comparison) Spreadability (comparison) pH blank control - Moderate good 7.0 bellflower to dissolve Moderate good 6.9 Ast...

Embodiment 3

[0050] Embodiment 3 A kind of drug compound for the treatment of pneumonia

[0051] 1. A drug complex for the treatment of pneumonia

[0052] 5 parts of Platycodon grandiflorum, 5 parts of aster, 5 parts of Baibu, 5 parts of Baiqian, 5 parts of licorice, 1 part of penetration enhancer azone, 2 parts of fusion agent propylene glycol.

[0053] 2. Precipitation state of raw materials of traditional Chinese medicine

[0054] Boil Platycodon grandiflorum, aster, 100-bud, Baiqian, and licorice until thick, cool, and add a blank control for easy observation; add penetration enhancer fusion agent successively, stir evenly, and observe the dissolution state and precipitation state of the drug. And compare the precipitation state with Experimental Example 1 and Example 2.

[0055] Table 3 Add propylene glycol to each raw drug hydrogel, the precipitation state of azone

[0056] drug Is it a gel viscosity drug status pH bellflower yes Moderate No obvious pre...

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PUM

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Abstract

The invention relates to the technical field of traditional Chinese medicines, in particular to a pharmaceutical composition for treating pneumonia as well as a preparation method and application thereof. The pharmaceutical composition for treating pneumonia comprises the following components: 2-10 parts of platycodon grandiflorum, 2-10 parts of aster, 2-10 parts of radix stemonae, 2-10 parts of cynanchum glaucescens, 2-10 parts of liquorice, 1-5 parts of a penetration enhancer, 1-2 parts of a preservative, 1-10 parts of a fusion agent and 1-5 parts of an emulsifier. The method comprises the following steps: soaking and draining the platycodon grandiflorum, the aster, the radix stemonae, the cynanchum glaucescens and the liquorice; adding water, performing heating to boiling, and performing filtering to obtain a primary liquid medicine and filter residues; adding water into the obtained decoction residues again, performing heating to boiling, and performing filtering to obtain a secondary liquid medicine; mixing the two liquid medicines, decocting the liquid medicines until thick, and performing cooling; and adding the penetration enhancer, the preservative, the fusion agent and the emulsifier, and performing uniform stirring and packaging. The composition has the effects of enhancing the lung function, reducing and relieving discomfort caused by lung injury after pneumonia, improving throat itching and cough symptoms existing after pneumonia improvement and relieving chest distress, and is beneficial to lung function recovery.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a drug compound for treating pneumonia and its preparation method and application. Background technique [0002] Pneumonia refers to the infectious inflammation of the alveoli, distal airways, and interstitium of the lungs, which can be caused by infection with bacteria, viruses, and other pathogens, among which bacterial and viral pneumonia are the most common. Patients often have typical symptoms such as fever, cough, and dyspnea. Viral pneumonia can spread through the air. [0003] Corona Virus Disease 2019 (COVID-19), referred to as "New Coronary Pneumonia", refers to the pneumonia caused by the 2019 novel coronavirus infection. [0004] The transmission routes of COVID-19 are mainly direct transmission, aerosol transmission and contact transmission. Direct transmission refers to the infection caused by the patient's sneezing, coughing, ta...

Claims

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Application Information

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IPC IPC(8): A61K36/904A61K47/10A61K47/22A61K47/14A61K47/20A61P11/00A61P31/14
CPCA61K36/27A61K36/28A61K36/346A61K36/484A61K36/904A61K47/10A61K47/14A61K47/20A61K47/22A61K2236/331A61K2236/39A61P11/00A61P31/14A61K2300/00
Inventor 邸航
Owner 辽宁钰航生物医疗科技有限公司
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