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Screening method of an intestinal flora transplantation donor

A screening method and technology of intestinal flora, applied in the field of biomedicine, can solve the problems of low professional level of screening methods and unsatisfactory screening results, and achieve the effects of increasing screening items, high stability, and avoiding waste of resources.

Pending Publication Date: 2020-09-18
厦门承葛生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the existing donor screening methods are customized for each research project. Generally speaking, the screening methods are not high in terms of coverage or professionalism, resulting in unsatisfactory screening results, and it is easy for some donors to be shoddy.

Method used

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  • Screening method of an intestinal flora transplantation donor
  • Screening method of an intestinal flora transplantation donor
  • Screening method of an intestinal flora transplantation donor

Examples

Experimental program
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Embodiment 1

[0033] A screening method for intestinal flora transplantation donors, comprising the following steps:

[0034] (1) Inform the donor of the concept of flora transplantation, its therapeutic value to patients, the indications of flora transplantation, and the current situation at home and abroad. Make sure that the donor has understood that there may be a risk of disease transmission in the flora transplantation, and let the donor understand that the information of the flora transplantation donor is very important for treatment, so he must accept a stricter medical screening than blood donation, and realize that it must be based on actual conditions Fill in the content of the questionnaire.

[0035] (2) Questionnaire survey: fill in the basic information (name, age, BMI, resident address, work, etc.), disease history, personal history, allergy history, gastrointestinal symptom score, diet, personality classification, etc. A total of more than 100 items content. Donors are on ...

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Abstract

The invention discloses a screening method of an intestinal flora transplantation donor. The method comprises the steps of firstly communicating with a donor, informing the donor of a flora transplantation concept and filling out notes of a questionnaire, and screening out qualified healthy donors through the processes of donor basic information registration, clinical evaluation, gastrointestinaltract pathogen detection and blood detection, wherein the expiration date of the donors is three months. And the healthy donor needs to be screened again in the gastrointestinal tract pathogenic bacteria detection and blood detection processes after three months, and only the donor meeting the requirements needs to be screened again and is the qualified donor. The invention aims to establish a scientific and reasonable screening method for the flora transplantation donors, which can improve the quality of healthy donors to ensure the safety and the effectiveness of transplantation to the maximum extent and provide basis and reference for the national establishment of relevant standards.

Description

technical field [0001] The invention relates to the technical field of biomedicine, in particular to a method for screening intestinal flora transplantation donors. Background technique [0002] Human Microbiota Transplantation (Human Microbiota Transplantation, HMT or FMT) refers to the intestinal flora of a healthy donor made into a suspension or capsule through an intelligent intestinal bacteria processing system, transplanted into the patient's gastrointestinal tract, and reconstructing the patient's normal intestinal function. Intestinal flora to achieve the treatment of intestinal and extraintestinal diseases. A donor is a person who potentially provides feces for microbiota transplantation. [0003] Bacterial flora transplantation is a new technology in my country, and the country has not yet formulated relevant donor screening standards. Existing donor screening methods are mostly customized for each research project. Generally speaking, the screening methods are n...

Claims

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Application Information

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IPC IPC(8): G16H20/00G16H70/20G16H50/30G16H50/70G16H10/20G16H10/60
CPCG16H20/00G16H70/20G16H50/30G16H50/70G16H10/20G16H10/60Y02A90/10
Inventor 肖传兴何剑全张帮周杨璐溪汪涵
Owner 厦门承葛生物科技有限公司
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