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Individualized brain function map construction method and system

A construction method and technology of brain function, applied in the field of image processing, can solve the problems of inability to construct, no curative effect, and large individual differences, and achieve the effect of good neural mechanism, good neural regulation and rehabilitation, and convenient diagnosis and treatment plan.

Pending Publication Date: 2020-08-25
SHENZHEN INST OF NEUROSCIENCE
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] However, the construction of brain function maps in related technologies is mostly based on the construction of group-level brain function maps, which cannot be constructed according to differences between individuals, so that they cannot reflect the functional positioning of individuals well. Due to individual differences in neuromodulation therapy Large, causing some users to have no curative effect after treatment

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  • Individualized brain function map construction method and system
  • Individualized brain function map construction method and system
  • Individualized brain function map construction method and system

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Embodiment 1

[0044] Embodiment 1 of the present invention provides a method for constructing an individualized brain function map, figure 1 A schematic flowchart of a method for constructing an individualized brain function map provided by an embodiment of the present invention, as shown in figure 1 As shown, the method includes the following steps:

[0045] S1100: Acquire the scanned image of the user.

[0046] In one embodiment, the resting-state fMRI scanning images of multiple groups of live test users are obtained, and the optional scanning parameters include: setting the scanning resolution to be 3 mm isotropic voxels, and the acquisition time points to be 250 etc., where the voxel contains a time series, which represents the change of the blood oxygen level-dependent signal in the voxel area over time.

[0047] S1200: Perform preprocessing on the scanned image. The preprocessing in this embodiment includes at least one of the following: head motion correction, image registration, ...

Embodiment 2

[0075] This embodiment provides a system for constructing an individualized brain function map, which is used to implement the method described in Embodiment 1, such as figure 2 As shown, it is a structural block diagram of an individualized brain function atlas construction system of this embodiment, including:

[0076] Acquisition unit 2100: used to acquire a set of scan images of the user, the scan images include: resting state functional magnetic resonance scan images;

[0077] Functional connection unit 2200: used to calculate the functional connection between each voxel in the brain region of interest in the scanned image and the whole brain voxel to obtain a functional connection matrix;

[0078] Similarity clustering unit 2300: used to calculate the similarity matrix of any two voxels according to the functional connectivity matrix, and perform similarity clustering on the data in the similarity matrix to obtain multiple sub-regions;

[0079] Construction unit 2400: ...

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Abstract

The invention discloses an individualized brain function map construction method and system, and relates to the image processing field, the method comprises the following steps: acquiring a scanning image of a user; calculating the functional connection between each voxel and the whole brain voxel in the interested brain region of the scanned image to obtain a functional connection matrix; and calculating a similarity matrix of any two voxels according to the function connection matrix, performing similarity clustering on data in the similarity matrix to obtain a plurality of sub-regions, andperforming brain region division on the user according to the sub-regions in combination with the scanning image to construct an individualized brain function map. By constructing the individualized brain function map, the brain function region of the individual can be positioned more accurately, so that the neural mechanism of the brain function of the individual can be better revealed, an individualized diagnosis and treatment scheme can be conveniently made, and nerve regulation, rehabilitation and the like can be better guided.

Description

technical field [0001] The present invention relates to the field of image processing, in particular to a method and system for constructing an individualized brain function atlas. Background technique [0002] Brain function atlas is the basis for studying brain function. In recent years, many studies have analyzed brain functions by constructing maps of the human brain. At the same time, neuromodulation technology has been widely used in the rehabilitation treatment of neuropsychiatric diseases and brain dysfunction in recent years. However, the core of precise neuromodulation is the precise positioning of brain functional areas, so the construction of brain function maps is the basis of these studies. The earliest brain functional atlas mainly used microscopic biohistochemical features such as cell structure, receptor distribution, and myelinization characteristics to divide the functional areas of the human brain. In recent years, more and more studies have confirmed t...

Claims

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Application Information

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IPC IPC(8): G06T7/00G06T7/33G06T5/00G06K9/62A61B5/055
CPCG06T7/0012G06T7/33A61B5/055A61B5/0033A61B5/0042G06T2207/20104G06T2207/30016G06F18/23213G06T5/70
Inventor 王骄健谭力海
Owner SHENZHEN INST OF NEUROSCIENCE
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