A drug for treating diabetic nephropathy ⅳ stage of kidney deficiency and collateral stasis type
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A technology for diabetic nephropathy and drugs, which is applied in drug combinations, urinary system diseases, metabolic diseases, etc., can solve problems such as the need to improve the curative effect, and achieve the effect of improving kidney function and reducing urinary protein
Active Publication Date: 2022-03-15
上海市嘉定区中医医院
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A large number of clinical studies have confirmed that traditional Chinese medicine has relatively obvious advantages in reducing the leakage of DN protein and improving renal function, especially according to the etiology and pathogenesis of DN, combined with clinical experience, an empirical prescription for the treatment of diabetic nephropathy (stage IV) with kidney deficiency and collateral stasis has been summarized. Zifen Yishen formula has achieved certain curative effect on improving patients’ symptoms such as backache, edema, dizziness and fatigue, but its curative effect still needs to be improved on improving patients’ renal function and reducing urinary protein
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[0010] The present invention is made by removing scrophulariaceae, atractylodes atractylodes, kudzu root, safflower, Alisma, golden cherry, and adding raw oyster, hedyotis, ghost arrow feather, salvia miltiorrhiza, and mulberry octopus on the basis of Ziyue Yishen prescription.
[0011] Zixi Yishen formula uses astragalus to nourish qi and nourish the root, and can also promote water; dogwood and yam strengthen the kidney and nourish the spleen, plus rehmannia glutinosa and crocodile to nourish the kidney and clear away heat, atractylodes invigorates the spleen and dampness, strengthens the root and lowers blood sugar, and kudzu root strengthens the spleen Yang; Gorgon fruit and golden cherry fruit are used together to invigorate the kidney and astringent essence; safflower promotes blood circulation and dredges collaterals; Modern pharmacological studies have shown that Astragalus has the functions of dilating blood vessels, increasing renal blood flow, inhibiting platelet agg...
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Abstract
A drug for treating kidney deficiency and collateral stasis type diabetic nephropathy stage IV, which consists of: 25-35g raw astragalus, 25-35g raw oyster, 25-35g Smilax, 25-35g Gorgon, 13-18g Hedyotis, ghost arrow Feather 8‑15g, Danshen 8‑13g, habitat 8‑12g, yam 7‑12g, dogwood 8‑12g, mulberry octopus 5‑12g. The present invention removes Scrophulariaceae, Atractylodes atractylodes, Radix Puerariae, Safflower, Alisma, and Rosa laevigata on the basis of Ziyue Yishen formula, and adds raw oyster, Hedyotis, ghost arrow feather, salvia miltiorrhiza, and mulberry octopus to strengthen blood circulation. Dispersing stagnation, removing blood stasis and dredging collaterals, clearing heat and detoxifying, so as to improve kidney function and reduce urine protein.
Description
technical field [0001] The invention relates to a medicine for treating the fourth stage of diabetic nephropathy of kidney deficiency and collateral stasis type, in particular a medicine prepared by adding and subtracting prescriptions on the basis of empirical prescription Zibi Yishen prescription. Background technique [0002] Diabetic nephropathy (DN) is a common and refractory microvascular complication of diabetes, and it is one of the main causes of death and disability in patients. Early detection of kidney damage, seeking active and effective treatment, and maximizing the control of DN (stage IV) disease are of great significance for delaying the progression of the disease and improving the quality of life of patients. Modern studies have shown that the occurrence and development of DN are closely related to protein non-enzymatic glycosylation, high blood viscosity, and hemodynamic abnormalities caused by high blood sugar. At present, the "Guidelines for the Prevent...
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