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Pulse-type time-lapse dispersion spectroscopy measurement method and device, and spectral imaging method and device

A spectral measurement and spectral imaging technology, applied in the field of spectral measurement and spectral imaging, can solve the problems of insufficient detection sensitivity of spectrometers and low spectral measurement efficiency, and achieve the effects of improving photon utilization, improving spectral measurement efficiency, and efficient utilization

Active Publication Date: 2021-03-30
HUAZHONG UNIV OF SCI & TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] Aiming at the defects of the prior art, the object of the present invention is to provide a pulse-type time-delay dispersion spectroscopy measurement method and device, aiming to solve the problem of low spectral measurement efficiency due to insufficient detection sensitivity of the spectrometer in the existing spectral measurement technology

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  • Pulse-type time-lapse dispersion spectroscopy measurement method and device, and spectral imaging method and device
  • Pulse-type time-lapse dispersion spectroscopy measurement method and device, and spectral imaging method and device
  • Pulse-type time-lapse dispersion spectroscopy measurement method and device, and spectral imaging method and device

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example 1

[0066] Example 1: An example of time-lapse dispersion spontaneous Raman spectroscopy measurement and spectral imaging based on pulse excitation.

[0067] figure 1 It is a principle diagram based on the time-delay dispersion spectroscopy measurement based on pulse excitation, wherein (a) is a schematic diagram of the spectrum obtained based on the existing spatial dispersion spectroscopy method, and (b) is the spectrum obtained according to the time-delay dispersion spectroscopy method provided by the present invention Schematic; from figure 1 In (a), it can be seen that the spectrum is dispersed in space, and many pixels of the camera array using the spectrometer are detecting different components of the spectrum, but the sensitivity of the array pixels is generally low, and the photon utilization rate is poor. From figure 1 In (b), it can be seen that the spectra are separated in the time dimension, the dotted line is the short pulse of excitation light, and the solid lin...

example 2

[0076] Example 2: Example of time-lapse dispersion CARS spectrum measurement and CARS spectrum imaging.

[0077] When the excitation laser is two synchronized and phase-locked pulse sources ω P , ω s , where ω P and ω s , usually pump light and Stokes light; when ω P and ω s When the energy difference between photons is consistent with the molecular vibrational energy level difference, an anti-Stokes photon ω CARS ,Such as figure 2 shown.

[0078] The embodiment of the present invention provides a method for time-lapse dispersion CARS spectrum measurement and CARS spectrum imaging, please refer to Figure 6 , and various system parameters can be selected according to the actual situation.

[0079]The pulse-type time-lapse dispersion spectroscopy imaging device provided by the embodiment of the present invention includes: a dual-channel pulsed laser generation module 200, a first power adjustment module 201, a second power adjustment module 202, an optical modulation m...

example 3

[0084] Example 3: A specific structural example of three delay dispersion modules.

[0085] The embodiment of the present invention provides three examples of generating time-delayed dispersion spectra. see reference Figure 8 , and various system parameters and methods can be selected according to the actual situation. The principle is as Figure 8 (a), the wavelength of the instantaneous spectrum generated by the pulsed laser is superimposed in time, and the photons in the spectrum can be separated in time and wavelength by using the method of time-delay dispersion and detected.

[0086] Figure 8 (b) shows the structure of the delay dispersion module based on the principle of fiber delay dispersion provided by the first embodiment. The fiber delay dispersion module includes: dispersion fiber 21, one end of which is connected to the photon collection module 106, and the other end is connected to the photoelectric The detection module 3 ; the photon collection module 106 ...

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Abstract

The invention belongs to the technical field of spectrum measurement and spectrum imaging. The invention discloses a pulse type time-delay dispersion spectrum measurement method and device and a spectrum imaging method and device; the spectrum measurement method includes: S1: Exciting the sample to be tested by a pulse laser and generating Instantaneous spectrum; S2: Time-delay processing of different photons in the instantaneous spectrum and separate them sequentially according to time sequence; S3: Use high-speed and high-sensitivity photodetectors to detect photons coming in the spectrum with time. The present invention uses instantaneous pulses to excite the sample, and concentrates the excited spectrum in the sample to the time period between the excitation light pulses, and then uses a single-channel high-sensitivity photodetector to realize high-efficiency direct measurement of the time-expanded spectrum , does not need to rely on multi-channel detection equipment to measure the spectrum; not only can efficiently use all photons in the spectrum, but also can increase the sensitivity of spectral measurement by orders of magnitude, thereby improving the efficiency of spectral measurement.

Description

technical field [0001] The invention belongs to the technical field of spectral measurement and spectral imaging, and more particularly relates to a pulse-type time-delay dispersion spectral measurement method and device, and a spectral imaging method and device. Background technique [0002] Spectroscopy has been widely used in many fields such as biology, chemistry, materials, medicine and industrial production because of its molecular specificity and other analysis and measurement advantages. Fluorescence spectroscopy originates from electronic state transitions in atoms and molecules, and can be applied to imaging, identification of atomic and molecular components, states, and fluorescent labeling. However, the line width of the fluorescence spectral lines is relatively wide, mostly in the range of 20nm to 100nm, which makes it difficult for fluorescence imaging technology to achieve more than five kinds of multicolor imaging. In contrast, Raman spectroscopy originates ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/65G01N21/63G01N21/01
CPCG01N21/01G01N21/63G01N21/65G01N21/658G01N2021/0112G01N2021/653
Inventor 王平李昊政
Owner HUAZHONG UNIV OF SCI & TECH
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