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Application of MSC in reducing cytokine storm influence

A cytokine and storm technology, applied in animal cells, vertebrate cells, cell dissociation methods, etc., to reduce damage and reduce the production of cytokines

Inactive Publication Date: 2020-07-31
HUNAN YUANPIN CELL TECH CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

At present, although many clinical trials have begun, there is currently no effective treatment for SARS-CoV-2 that can reduce the impact of cytokine storms on humans

Method used

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  • Application of MSC in reducing cytokine storm influence
  • Application of MSC in reducing cytokine storm influence
  • Application of MSC in reducing cytokine storm influence

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Embodiment Construction

[0025] In order to enable those skilled in the art to better understand the technical solutions of the present invention, the present invention will be further described in detail below in conjunction with the accompanying drawings.

[0026] It should be noted that the original treatment plan mentioned in the present invention refers to the treatment plan adopted in the new coronavirus pneumonia diagnosis and treatment plan issued by the General Office of the National Health Commission and the Office of the State Administration of Traditional Chinese Medicine. MSC+ means the MSC treatment group , MSC- means the group without MSC treatment, Health means the healthy group.

[0027] Such as figure 1 As shown, in order to study the application of MSC for alleviating the impact of cytokine storm, the present invention provides a kind of specific steps for the application of MSC for alleviating the impact of cytokine storm in patients with viral infection, including:

[0028] S1, p...

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Abstract

The invention specifically discloses an application of MSC in reducing cytokine storm influence, in particular to an application of MSC in reducing cytokine storm influence of a viral infection patient, and relates to the technical field of biomedical engineering. A prepared MSC preparation is added into an MSC treatment group to carry out combined treatment on the viral infection patient, AP-1 / JNK pathway activation can be effectively inhibited, the generation of cytokines is reduced, and the formation of cytokine storms is inhibited, so that the injury of the cytokine storms to the tissues in the body of the patient can be effectively reduced by combined treatment of the MSC treatment group.

Description

technical field [0001] The invention relates to the technical field of biomedical engineering, in particular to an application of MSCs for alleviating the impact of cytokine storm. Background technique [0002] Viral infection refers to an infectious disease caused by a virus that can parasitize and reproduce in the human body. The main manifestations are systemic poisoning symptoms such as fever, headache, and general malaise, and local symptoms caused by inflammation and damage caused by the virus host and invading tissues and organs. Viral infections in the human body are divided into recessive infections, dominant infections, and lentiviral infections. Infection in most cases is recessive infection (refers to human body infection virus, no symptoms, but can produce specific antibodies). A few are overt infections (refers to the emergence of symptoms after the human body is infected with the virus). Among the overt infections, most viral infections manifest as acute in...

Claims

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Application Information

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IPC IPC(8): A61K35/28A61P31/12A61P31/14C12N5/0775
CPCA61K35/28A61P31/12A61P31/14C12N5/0665C12N2509/00C12N2509/10
Inventor 李莉王健郑春兵陈玲玲文乐周艺林
Owner HUNAN YUANPIN CELL TECH CO LTD
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