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Optical coherence elastography (OCE) device

An elastography and optical coherence technology, applied in measurement devices, material analysis by optical means, scientific instruments, etc., can solve the problems of low elastic vibration sensitivity of biological tissues, and achieve the effect of improving sensitivity

Active Publication Date: 2020-07-31
BEIJING INFORMATION SCI & TECH UNIV
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  • Claims
  • Application Information

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Problems solved by technology

[0005] However, in the process of practical application, it is found that the optical coherent elastography system excited by the acoustic radiation force in the prior art is limited by the problems existing in the system structure, and the sensitivity to elastic vibration detection of biological tissues is generally low.

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  • Optical coherence elastography (OCE) device
  • Optical coherence elastography (OCE) device
  • Optical coherence elastography (OCE) device

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Embodiment Construction

[0046] As mentioned in the background art, the optical coherent elastography system excited by acoustic radiation force in the prior art is limited by the problems in the system structure, and the detection sensitivity for elastic information of biological tissues is generally low, or it is not convenient for sample measurement.

[0047] Specifically, since the optical path of the optical coherence tomography unit and the acoustic path of the acoustic radiation force excitation unit cannot block each other, such problems as Figure 1-Figure 4 Four structures are shown.

[0048] refer to figure 1 , figure 1 In the optical coherent elastography system excited by the acoustic radiation force shown, the ultrasonic beam emitted by the acoustic radiation force excitation unit (including the host computer, waveform generator, amplifier and ultrasonic transducer) and the optical coherence tomography unit ( figure 1 The figure only shows the optical path of the sample, including c...

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Abstract

The invention discloses an optical coherence elastography (OCE) device. The device induce vibration by using ultrasound beams in a sample, vibration in the sample is detected by an imaging device, coupling of a detection light beam and the ultrasound beam is realized through a coupling unit, particularly, the coupling unit comprises a sound reflection surface and a light incidence surface, the sound reflection surface has an optical transparency characteristic and a sound reflection characteristic, so that the detection light beam from the light incidence surface can be transmitted to the to-be-detected sample through the light incidence surface and the sound reflection surface, the ultrasound beam from the light incidence surface is reflected by the sound reflection surface and then transmitted to the to-be-detected sample with the detection light beam in the same direction, same-side incidence of the ultrasound beam and the detection light beam is realized, and the vibration detection sensitivity can be improved. Besides, the device requires no preparation of an annular ultrasound transducer, cannot limit the spreading range of the detection light beam or ultrasound, and bad effects of weaker sound field intensity or light field intensity on the detection sensitivity are avoided.

Description

technical field [0001] The present application relates to the field of imaging technology, and more specifically, relates to an optical coherent elastic imaging device. Background technique [0002] Differences in the elasticity of biological tissues originate from differences in composition, structure, and interactions at the biomolecular, cellular, and tissue levels. Elasticity imaging of biological tissue uses a medical imaging platform, combined with the principle of elasticity measurement, to analyze the mechanical elastic properties of the tissue, and reconstruct the elastic distribution image of the tissue in a plane or space. [0003] In elastography, the elastic vibration of the tissue is first induced by external force, then the elastic vibration of the tissue is detected by medical imaging methods, and finally the elastic mechanical properties of the tissue are quantitatively or qualitatively analyzed through the calculation of the elastic vibration. Optical Cohe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00A61B8/00G01N21/84G01N29/04
CPCA61B5/0066A61B8/485A61B8/488A61B8/4483A61B8/4488G01N29/045G01N21/84
Inventor 朱疆杨强祝连庆樊凡刘鉴霆
Owner BEIJING INFORMATION SCI & TECH UNIV
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