Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Establishment of intestinal tract metabolic map of longevity family and application of intestinal tract metabolic map in field of aging health

A technology of intestinal health and metabolites, applied in the field of establishment of intestinal metabolic map, can solve the problems that fecal metabolome research has not been reported, and achieve the effect of shortening the pretreatment time and rapid extraction

Active Publication Date: 2020-07-28
广州市华永睿健生物科技有限公司
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the faecal metabolome study of long-lived populations has not been reported

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Establishment of intestinal tract metabolic map of longevity family and application of intestinal tract metabolic map in field of aging health
  • Establishment of intestinal tract metabolic map of longevity family and application of intestinal tract metabolic map in field of aging health
  • Establishment of intestinal tract metabolic map of longevity family and application of intestinal tract metabolic map in field of aging health

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] The inventors identified the metabolic markers based on the analysis of metabolites in stool samples from a total of 44 cases of longevity families (85.2±12.5) and 127 cases of non-longevity families (82.2±10.8).

[0034] Among them, the relative abundance of differential metabolites in the longevity family and non-longevity family groups is shown in Table 2.

[0035] Table 2 The relative abundance of differential metabolites in the longevity family and non-longevity family groups

[0036]

[0037]

[0038] By comparing the abundance of metabolites in feces samples of individuals from longevity families and individuals from non-longevity families (Table 2), betulin (Betulin), (R)-(+)-2-pyrrolidone-5-carboxylic acid ( (R)-(+)-2-Pyrrolidone-5-carboxylic acid), α-dimethyl valeric acid (α-dimethyl valeric acid), R-(-)-mandelic acid (R-(-)-Mandelic acid ), aminohippuric acid (Aminohippuric acid), 3-hydroxy-tetradecanoic acid (3-hydroxy-tetradecanoic acid) in the long-...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses establishment of an intestinal tract metabolic map of a longevity family and application of the intestinal tract metabolic map in the field of aging health. Research is carriedout according to excrement metabolites of different long-life individuals; new research is carried out on intestinal health and long life from the perspective of excrement metabolites, so that the microbial community metabolic profile change of the intestinal tracts of family type long-life people and metabolic characteristics stably influencing the life of people can be observed more comprehensively, meanwhile, a new method and thought are provided for mechanism research of interaction between metabolites of intestinal microorganisms of the family type long-life people and organisms, and a new thought is provided for an anti-aging treatment mechanism.

Description

technical field [0001] The invention relates to the field of molecular biomedicine, in particular to the establishment of intestinal metabolic maps of longevity families and its application in the field of aging health. Background technique [0002] The study of aging and longevity has always been a hot issue in the field of life sciences, but it has not yet been elucidated. Aging is influenced by genetics, age, living environment, diet, etc., and is a complex multi-factor process. Aging is bound to be accompanied by changes in the metabolic state. The level of metabolites in the body plays an important role in health and longevity. Many diseases and inflammations are related to metabolic imbalances. At present, the research on body health and disease focuses on the field of intestinal microecology. During the co-evolution process of intestinal flora and host, the composition and diversity of the flora are affected by internal factors of the host or external environmental f...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/50
CPCG01N33/50
Inventor 陈涛马燕陆正齐陆勇军伍星张召
Owner 广州市华永睿健生物科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com