Preparation device and preparation method of medicine administration microneedle

Abstract

The invention discloses a preparation device and preparation method of a medicine administration microneedle. The preparation device comprises an upper plate, a template, a soft liner, an isolation layer and a bottom plate, wherein the upper plate, the template, the soft liner, the isolation layer and the bottom plate are sequentially arranged from top to bottom and all use heat-resistant materials; the isolation layer uses an air-permeable liquid-tight material; micro hole regions corresponding to needles of the microneedle are formed on the template; a plurality of micro holes are formed ineach micro hole region; the micro holes are through holes formed in the template; step holes with the larger upper sides and the smaller lower sides are formed in positions, corresponding to the microhole regions, on the upper plate; a compression mechanism is arranged on the upper plate; the compression mechanism comprises compression heads used for being inserted into big sections of the upperparts of the corresponding step holes; and the dimension of each compression head is smaller than the dimension of the small section of the lower part of the corresponding step hole. The preparation device of the microneedle provided by the invention has the advantages that the use is convenient; the operation process is simple; the industrialized mass production of the microneedle can be realized; in addition, thermoplastic raw materials can be easily obtained; and the production cost of the microneedle can be reduced.

Description

technical field [0001] The invention relates to a preparation device and a preparation method of a drug delivery microneedle, belonging to the technical field of medical equipment. Background technique [0002] As a new type of transdermal drug delivery, microneedle transdermal drug delivery combines the advantages of subcutaneous injection drug delivery and transdermal patch drug delivery. It is not only painless and minimally invasive, but also has high drug absorption efficiency. In addition, patients can self-administer microneedle administration, which is convenient and safe. Therefore, microneedle transdermal drug delivery technology has gained widespread attention since its inception. The basic structural form of drug delivery microneedles is: on a substrate (such as but not limited to flat plate, curved plate, etc.) of suitable thickness and suitable shape (such as but not limited to round, square, etc.), a group of varying numbers of microneedles. The basic use p...

AI Technical Summary

Problems solved by technology

[0007] The purpose of the present invention is to provide a preparation device and preparation method of microneedles for drug administration, so as to solve the technical problems of the microneedle production process in the prior art, which are cumbersome, high cost, and unable to achieve mass production

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