Application of GHRH-A in preparation of drugs for preventing and treating ischemic brain infarction
A GHRH-A, ischemic brain technology, applied in drug combinations, pharmaceutical formulations, cardiovascular system diseases, etc., can solve the problem of low nerve cell regeneration rate, and achieve the effect of increasing brain weight and improving neurobehavioral performance
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[0054] Combine the following Figure 1~20 , the content of the present invention is described in detail through specific embodiments.
[0055] The invention relates to the application of growth hormone-releasing hormone receptor agonist MR-409 in the preparation of medicines for preventing and treating ischemic stroke:
[0056] 1. Experimental materials:
[0057] C57BL / 6 mice, male, weighing 22-25 g, animal certificate number: purchased from the Experimental Animal Center of Shenyang Medical College. Adult SD rat, neural stem cells in the hippocampus. MR-409 was provided by the laboratory of Professor Andrew Schally (1977 Nobel Prize winner in medicine) at the University of Miami (Miami, FL, USA), with a purity of 10% 1,2-propanediol. Concentration reserve.
[0058] ,experimental method:
[0059] 2.1 Experimental grouping and administration
[0060] 1) The experimental animals were C57BL / 6 mice, weighing 22-25 g, and divided into sham operation group, model group, MR-409...
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