Preparation for controlling ovulation of equus animals and method for controlling ovulation

A preparation and animal technology, applied in the field of animal breeding, can solve the problems of soaring international donkey skin prices, the difficulty of applying the method for controlling ovulation of mares to female donkeys, etc., and achieve the effects of low production cost, low price of raw materials, and improved pregnancy rate.

Active Publication Date: 2020-05-29
CHINA AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the demand for live donkeys is increasing day by day. The donkey-hide gelatin market alone currently needs 4 million donkey skins per year, while the total stock of donkeys in China is less than 5 million. The supply is in short supply, and we have to rely

Method used

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  • Preparation for controlling ovulation of equus animals and method for controlling ovulation
  • Preparation for controlling ovulation of equus animals and method for controlling ovulation
  • Preparation for controlling ovulation of equus animals and method for controlling ovulation

Examples

Experimental program
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Effect test

Embodiment 1

[0047] The preparation of the ovulation fluid of embodiment 1 control animal ovulation

[0048] 1. Ovulation fluids containing different sustained-release carriers and their application effects

[0049] (1) Preparation of ovulation fluid containing different slow-release carriers

[0050] The following A~J respectively provide the ovulation fluid containing different slow-release carriers in this embodiment:

[0051] A. Weigh 0.1g of deserelin and 2.0g of trehalose, add ethanol to fully dissolve to obtain a gonadotropin-releasing hormone solution; weigh 700g poly(DL-lactide-co-glycolide), add ethanol to fully Dissolve to obtain a slow-release carrier solution; mix the two solutions evenly, make up to 1000 g with ethanol, and obtain 0.01% deserelin ovulation solution.

[0052] B. Weigh 0.1g of deserelin and 2.0g of trehalose, add ultrapure sterile water to fully dissolve to obtain a gonadotropin-releasing hormone solution; weigh 700g of polysucrose, add ultrapure sterile wate...

Embodiment 2

[0098] The ovulation control of embodiment 2 Akhate gold (sweat blood) horse and the effect of natural mating

[0099] Near Hohhot, Inner Mongolia, 32 Ahatekin mares aged 3 to 10 years old were selected, with moderate body condition, healthy and normal fecundity. They were raised in pens with an outdoor playground, had free access to water, and were fed green hay (leymus chinensis and alfalfa) twice. From April to June, test the stallion with the stallion every morning from 8:00 to 10:00. If the stallion stands still after approaching, lifts its tail, opens its vulva frequently, and discharges urine, it means that the mare is ready for breeding. At the same time, use a B-ultrasound probe to check the follicles and uterine edema across the rectal wall. On the B-ultrasound machine, the "cross method" is used to measure the diameter of the follicle, that is, measure a maximum value in the longitudinal direction, then cross vertically, measure a maximum value in the horizontal di...

Embodiment 3

[0102] Example 3 Ovulation control of Mongolian horses and the effect of using frozen semen for breeding

[0103] In the vicinity of Shenyang City, Liaoning, 35 mares of Mongolian horses aged 3 to 8 were selected, with moderate fat condition, healthy and normal fecundity. They were reared in pens with an outdoor sports field, free to drink water, and fed green hay (leymus chinensis and alfalfa) twice. From June to August, from 8:00 to 10:00 in the morning, B-ultrasound rectal examination was used to check the development of follicles in the horse herd. On the B-ultrasound machine, the "cross method" is used to measure the diameter of the follicle, that is, measure a maximum value in the longitudinal direction, then cross vertically, measure a maximum value in the horizontal direction, add the two values ​​and take the average value, which is the diameter of the follicle. When the diameter of the follicle reaches more than 35mm and the edema of the endometrium is obvious, the ...

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Abstract

The invention provides a preparation for controlling ovulation of equus animals and a method for controlling ovulation. The preparation comprises a gonadotropin-releasing hormone analogue and a slow release carrier being degradable in bodies of animals. Gonadotropin-releasing hormones are prepared into a slow release preparation, so that the half-life period in bodies can be effectively prolonged,and the preparation can exert the effect of promoting ovulation efficiently and stably for a long time. The preparation disclosed by the invention is injected, 96% or above of female horses and female donkeys can ovulate within 48 hours, and the ovulation time of 96% or above of the animals can be controlled to be within 8 hours, so that efficient ovulation control of the equus animals can be realized, and the breeding pregnancy rate of the equus animals can be notably increased. The ovulation control method is simple to operate, low in cost and notable in control effects, does not cause anyadverse effects on animals and products thereof, can be widely applied to natural mating breeding, artificial insemination, embryo transplanting and timing insemination of the equus animals, and has broad market prospects.

Description

technical field [0001] The invention relates to the field of animal reproduction, in particular to a preparation for controlling ovulation of equine animals and a method for controlling ovulation. Background technique [0002] With the development of the national economy and the improvement of people's living standards, industries such as horse breeding, training, competition and leisure and entertainment have developed rapidly, and the market potential is huge. In recent years, its output value has shown a linear upward trend. It is estimated that by 2030, China's horse industry The total output value will reach trillions. At present, there are about 6 million horses in stock in China, but the quality is uneven, and there is a lack of special speed, endurance performance, equestrian and leisure riding breeds, which cannot meet the current market demand. Therefore, the breeding of characteristic thoroughbred horses is one of the problems to be solved urgently at present. A...

Claims

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Application Information

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IPC IPC(8): A61K38/09A61K47/36A61K47/34A61K47/10A61K47/26A61P15/08A61D19/02
CPCA61K38/09A61K47/36A61K47/34A61K47/10A61K47/26A61P15/08A61D19/027
Inventor 曾申明杨峰
Owner CHINA AGRI UNIV
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