Propolis composition and instrument thereof and application thereof in wound treatment

A composition and propolis technology, applied in the field of medical devices, can solve problems such as hindering the wound healing process, increasing the risk of infection and sepsis, and achieving the effects of shortening time, promoting healing, and improving air and moisture permeability.

Inactive Publication Date: 2020-02-21
浙江晟健医疗健康产业发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Not only does dead or devitalized tissue impede the wound healing process, but dead tissue or foreign material provides an environment for bacterial growth, increasing the risk of infection and sepsis

Method used

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  • Propolis composition and instrument thereof and application thereof in wound treatment
  • Propolis composition and instrument thereof and application thereof in wound treatment

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1 prepares propolis composition

[0030] In parts by weight, 50w / w% of propolis, 15w / w% of sodium alginate and 25w / w% of carboxymethyl cellulose were mixed into a paste to obtain the propolis composition of this embodiment.

Embodiment 2

[0031] Embodiment 2 prepares dressing

[0032] The obtained propolis composition is loaded on gauze (or non-woven fabric) to make a dressing, specifically, the paste-like propolis composition is applied to gauze (or non-woven fabric), so that the propolis composition on the gauze (or non-woven fabric) surface A propolis composition layer with a thickness of 0.2 mm to 2 mm is formed.

Embodiment 3

[0034] Apply the prepared propolis composition to the wound surface of the test animal as follows.

[0035] 1. Prepare experimental equipment and reagents. Tweezers, scissors, ruler, alcohol cotton balls, depilatory cream, chloral hydrate, syringes, shaving machines, animal scales, cameras.

[0036] 2. The mice were divided into 3 groups: negative control group, 50% propolis composition group and 100% propolis composition group, with 6 mice in each group.

[0037] 3. Inject the mice with anesthesia. The mice were weighed and injected with chloral hydrate at a dose of 1.0ml / 20g.

[0038] 4. Depilation of mice. First use a hair removal machine to remove the long hair on the back of the mouse, and then apply the depilatory cream evenly on the back of the mouse for hair removal.

[0039] 5. Cut the wound. Cut a circular wound with a diameter of 6 mm in the clean part of the back of the mouse.

[0040] 6. Observe and count the wound healing area.

[0041] The composition conta...

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Abstract

The invention relates to a propolis composition, which comprises 50%+ / -5% of propolis, 15%+ / -5% of sodium alginate and 25%+ / -5% of carboxymethyl cellulose. The tests prove that the propolis composition disclosed by the invention is beneficial to wound healing after being coated on a wound, the wound healing area in unit time is remarkably increased, wound healing is remarkably promoted, and the wound healing time is shortened.

Description

technical field [0001] The invention relates to a medical device, in particular to a dressing made of a propolis composition as an active ingredient and its application in wound treatment. Background technique [0002] Trauma is the destruction and damage of human tissues or organs caused by mechanical factors, such as: trauma, burns, decubitus ulcers, diabetic feet, and postoperative incisions that are difficult to heal. Trauma not only has a high incidence rate, but also varies greatly in degree. The injury can be serious and complicated, and even endanger the life of the wounded. [0003] Not only does dead or devitalized tissue impede the wound healing process, but dead tissue or foreign material provides an environment for bacterial growth, increasing the risk of infection and sepsis. On the one hand, in order for the medical personnel to correctly assess the wound formed on the tissue and also to be able to see the tissue structure of the wound bed clearly, it is nece...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/44A61L15/40A61L15/28
CPCA61L15/28A61L15/40A61L15/44A61L2300/232A61L2300/412A61L2300/45C08L5/04C08L1/286
Inventor 张帅杨杨
Owner 浙江晟健医疗健康产业发展有限公司
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