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Application of morinda officinalis extract in preparation of skeletal muscle fatigue resisting agent

A technology of Morinda officinalis extract and skeletal muscle fatigue, which is applied in the direction of anti-toxins, drug combinations, plant raw materials, etc., can solve the problems of body harm, achieve the effects of changing nutrient metabolism, prolonging time, and improving anti-fatigue activity

Inactive Publication Date: 2020-01-21
ZHEJIANG OCEAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to overcome the problem that anti-fatigue drugs in the prior art contain ingredients such as stimulants, which will cause certain harm to the body after taking them. It is urgent to find a safe and efficient anti-fatigue drug with less side effects and no stimulants. Provides an application of Morinda officinalis extract in the preparation of anti-skeletal muscle fatigue agent. The traditional Chinese herbal medicine Morinda officinalis extract is used as the main component in the anti-skeletal muscle fatigue agent. The extract of Morinda officinalis can stimulate peroxidation in skeletal muscle The generation of hydrogenase increases the activity of catalase, prolongs the time for skeletal muscle to reach the fatigue state, effectively improves the anti-fatigue activity of skeletal muscle, and does not need to add stimulants. It is a safe and efficient anti-fatigue drug

Method used

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  • Application of morinda officinalis extract in preparation of skeletal muscle fatigue resisting agent
  • Application of morinda officinalis extract in preparation of skeletal muscle fatigue resisting agent
  • Application of morinda officinalis extract in preparation of skeletal muscle fatigue resisting agent

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Effect test

Embodiment 1

[0032] An application of Morinda officinalis extract in the preparation of anti-skeletal muscle fatigue agent, the components of anti-skeletal muscle fatigue agent include 0.1mg / mL Morinda officinalis extract, 6mg / mL NaCl, 0.13mg / mL KCl, 0.1mg / mL NaHCO 3 , 0.1mg / mL CaCl 2 , 0.01mg / mL NaH 2 PO 4 , 1mg / mL glucose and water.

[0033] The preparation method of Morinda officinalis extract comprises the following steps:

[0034] (1) Rough extraction: add water to Morinda officinalis medicinal material powder, the mass ratio of Morinda officinalis medicinal material powder to water is 1:5, 800W, 40Hz, after ultrasonic extraction for 40min, filter it once with filter paper with a pore size of 30μm Filtrate and primary filter residue, the primary filter residue is extracted three times in the same way, the filtrate obtained three times is mixed with the primary filtrate, concentrated and dried to obtain the crude extract of Morinda officinalis;

[0035] (2) Refining extraction: add...

Embodiment 2

[0037] An application of Morinda officinalis extract in the preparation of anti-skeletal muscle fatigue agent, the components of anti-skeletal muscle fatigue agent include 0.5mg / mL Morinda officinalis extract, 6.5mg / mL NaCl, 0.14mg / mL KCl, 0.2 mg / mL NaHCO 3 , 0.2mg / mLCaCl 2 , 0.01mg / mL NaH 2 PO 4 , 2mg / mL glucose and water.

[0038] The preparation method of Morinda officinalis extract comprises the following steps:

[0039] (1) Rough extraction: add water to Morinda officinalis medicinal material powder, the mass ratio of Morinda officinalis medicinal material powder to water is 1:8, 900W, 50Hz, after ultrasonic extraction for 30min, filter it once with filter paper with a pore size of 40μm Filtrate and primary filter residue, the primary filter residue is extracted three times in the same way, the filtrate obtained three times is mixed with the primary filtrate, concentrated and dried to obtain the crude extract of Morinda officinalis;

[0040] (2) Refining extraction: ...

Embodiment 3

[0042] An application of Morinda officinalis extract in the preparation of anti-skeletal muscle fatigue agent, the components of anti-skeletal muscle fatigue agent include 2.5mg / mL Morinda officinalis extract, 7mg / mL NaCl, 0.15mg / mL KCl, 0.3mg / mL NaHCO 3 , 0.3mg / mL CaCl 2 , 0.02mg / mL NaH 2 PO 4 , 3mg / mL glucose and water.

[0043] The preparation method of Morinda officinalis extract comprises the following steps:

[0044] (1) Rough extraction: add water to Morinda officinalis medicinal material powder, the mass ratio of Morinda officinalis medicinal material powder to water is 1:10, 1000W, 60Hz, after ultrasonic extraction for 20min, filter once with filter paper with a pore size of 50μm Filtrate and primary filter residue, the primary filter residue is extracted three times in the same way, the filtrate obtained three times is mixed with the primary filtrate, concentrated and dried to obtain the crude extract of Morinda officinalis;

[0045] (2) Refining extraction: ad...

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Abstract

The invention relates to a traditional Chinese medicine extract and an application field thereof, and discloses application of a morinda officinalis extract in preparation of a skeletal muscle fatigueresisting agent. The skeletal muscle fatigue resisting agent comprises components of 0.1-2.5 mg / mL of the morinda officinalis extract, 6-7 mg / mL of NaCl, 0.13-0.15 mg / mL of KCl, 0.1-0.3 mg / mL of NaHCO3, 0.1-0.3 mg / mL of CaCl2, 0.01-0.02 mg / mL of NaH2PO4, 1-3 mg / mL of glucose and water. A traditional Chinese herbal medicine, namely, the morinda officinalis extract is used as the main component ofthe morinda officinalis extract, the time for skeletal muscle to reach the fatigue state can be prolonged, the fatigue resisting activity of the skeletal muscle can be effectively improved, besides, no stimulant is added, and the skeletal muscle fatigue resisting agent is a safe and efficient anti-fatigue drug.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine extracts and their applications, in particular to the application of Morinda officinalis extracts in the preparation of anti-skeletal muscle fatigue agents. Background technique [0002] In modern society, with the continuous increase of various external pressures and psychological pressures, all age groups begin to show different levels of fatigue. In mild cases, symptoms of sleepiness may appear, but it can be relieved by supplementing nutrition, rest and sleep; in severe cases, endocrine disorders, organ lesions and even mental diseases may occur, which seriously threaten people's physical and mental health. With the development of science, various researches on fatigue are being deepened, and anti-fatigue drugs are also constantly pouring out. But because some anti-fatigue drugs contain ingredients such as stimulants, which may cause certain harm to the body, the application of thi...

Claims

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Application Information

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IPC IPC(8): A61K36/746A61P39/00A61P21/00
CPCA61K36/746A61K2236/331A61K2236/39A61P21/00A61P39/00
Inventor 赵玉勤
Owner ZHEJIANG OCEAN UNIV
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