Microsphere screen, production-type high-efficiency microsphere collection device and application thereof
A collection device and microsphere technology, which is applied in the direction of filtration and separation, fixed filter elements, chemical instruments and methods, etc., can solve the problems of increased filtration resistance, stuck sieve holes, and decreased sieving efficiency, so as to reduce energy consumption. Consumption, meeting production requirements, high removal efficiency
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Embodiment 1
[0043] The present invention provides a microsphere screen, comprising a vertical screen 4 and a split flow unit 5 fixed in the vertical screen 4, see figure 1 .
[0044] In the embodiment of the present application, each branching unit 5 is composed of a left-handed unit piece 5a and a right-handed unit piece 5b; preferably, the number of five branching units is 15-20.
Embodiment 2
[0046] figure 1 It is a schematic diagram of the device of the present invention. A production-type high-efficiency microsphere collection device provided by the present invention includes a vertical screen 4, a flow diversion unit 5, a collection unit 6, a sealed casing 9, and a liquid discharge unit. The vertical screen The net 4 is penetrated and fixed in the sealed casing 9 to form a screening chamber, the upper end of the screening chamber is the feed liquid inlet 1 for feeding, the lower end of the screening chamber is connected to the collection unit, and the side wall of the screening chamber is connected to the drain unit.
[0047] In the embodiment of the present application, each branching unit 5 is composed of a left-handed unit piece 5a and a right-handed unit piece 5b; preferably, the number of five branching units is 15-20.
[0048] In the embodiment of the present application, the upper end of the screening chamber is sequentially connected to the connection f...
Embodiment 3
[0053] The risperidone microspheres were collected by the above-mentioned device, and the target particle size was 25-150 μm. The volume of feed liquid is 500L, and the solid content accounts for about 0.25%. The microsphere collection device is placed in the B-level area. The feed liquid inlet of the microsphere collection device is connected to the microsphere preparation system through the connecting flange, and the concentrated liquid outlet is connected to the 2L stainless steel barrel through the AB valve. A 150μm screen is installed at the downstream end of the microsphere preparation system to pre-filter large-particle microspheres (accounting for <1%). The pre-filtered feed liquid is pressed into the collection device, and the flow rate is controlled to stabilize at 8-12L / min. When the liquid flows through the vertical sieve (the sieve diameter is 25 μm), tangential flow filtration occurs under the action of the splitter unit, small particles and solutions pass throug...
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