Turner syndrome bone health evaluation system and establishment method thereof

Abstract

The invention relates to a Turner syndrome bone health evaluation system and an establishment method thereof. The establishment method comprises the steps: setting a plurality of parameter acquisitionunits, setting a parameter processing unit, setting a judgment unit, setting an output unit and the like. By applying bone quantitative ultrasonic detection data obtained by an ultrasonic bone mineral density instrument to dozens of TS patients, it is found that the ultrasonic propagation speed and amplitude attenuation of the TS patients have positive and negative correlation with ages and haveno correlation with karyotypes of chromosomes. And further research shows that other data results are similar to bone quantitative ultrasonic detection data feedback results, have certain correlationwith the bone mineral density of the TS patient and have different amplitudes of influence on the bone health state of the TS patient. The research results are integrated, the advantages and disadvantages of X-ray absorption measurement, ultrasonic measurement, CT and other detection methods are combined, a multidirectional multi-systematic TS bone health evaluation system is established, and theestablishment of an early prediction, early intervention and early treatment medical mode for TS bone health decline is particularly important.

Description

technical field [0001] The invention relates to the field of disease health status assessment, in particular to a Turner syndrome bone health assessment system and its establishment method. Background technique [0002] Studies have shown that TS (Turner’s Syndrome, Turner syndrome) patients have a 25% higher risk of fracture than the normal population. How to scientifically evaluate the bone health of TS patients to reduce osteoporosis is a hot spot in the industry. At present, the evaluation results of bone quality in TS patients are mixed. Some scholars have used dual-energy X-ray absorptiometry (DEXA) to study and found that the bone mineral density (BMD) of TS patients with cortical bone and cancellous bone decreased in different degrees. No change. It has been reported that high-resolution quantitative computed tomography (QCT) can be used to observe abnormal bone microstructure and bone strength in TS patients compared with normal people, which is the reason for the ...

AI Technical Summary

Problems solved by technology

[0003] Because there are many differences in the traditional evaluation indicators and results of bone health in patients with Turner syndrome, there is no relatively reliable evaluation system to evaluate the bone health status of patients with Turner syndrome.

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